At the Global Liver Institute, we believe it all starts with a patient. What happens when a liver patient, one of the ½ billion people living with conditions that often go undiagnosed, untreated, or misdiagnosed, mistreated, and stigmatized, brings the challenges of liver patients front and center? And what happens when a patient then leads a discussion with world experts in policy, research, clinical care, and wellness on ways to overcome these challenges? GLI LIVE started in March 2020, as a COVID-19 response program for liver patients. It has now evolved into so much more: a weekly educational show with tailored information for patients living with liver diseases on a variety of timely topics.