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محتوای ارائه شده توسط Danny Lennon. تمام محتوای پادکست شامل قسمتها، گرافیکها و توضیحات پادکست مستقیماً توسط Danny Lennon یا شریک پلتفرم پادکست آنها آپلود و ارائه میشوند. اگر فکر میکنید شخصی بدون اجازه شما از اثر دارای حق نسخهبرداری شما استفاده میکند، میتوانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
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Sigma Nutrition Radio
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محتوای ارائه شده توسط Danny Lennon. تمام محتوای پادکست شامل قسمتها، گرافیکها و توضیحات پادکست مستقیماً توسط Danny Lennon یا شریک پلتفرم پادکست آنها آپلود و ارائه میشوند. اگر فکر میکنید شخصی بدون اجازه شما از اثر دارای حق نسخهبرداری شما استفاده میکند، میتوانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.
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محتوای ارائه شده توسط Danny Lennon. تمام محتوای پادکست شامل قسمتها، گرافیکها و توضیحات پادکست مستقیماً توسط Danny Lennon یا شریک پلتفرم پادکست آنها آپلود و ارائه میشوند. اگر فکر میکنید شخصی بدون اجازه شما از اثر دارای حق نسخهبرداری شما استفاده میکند، میتوانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.
…
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Sigma Nutrition Radio


Every five years, the U.S. Dietary Guidelines are updated based on the latest scientific evidence to help shape national nutrition recommendations. A panel of experts was assembled to review the existing research, evaluate new findings, and provide recommendations that will inform the next edition of the guidelines. One of the committee members involved in this process is Professor Christopher Gardner, a leading nutrition scientist at Stanford University, who joins us to share key insights from the committee’s work. In this discussion, Professor Gardner provides an inside look into how the committee evaluated dietary patterns, the role of plant-based proteins, and the ongoing debate surrounding ultra-processed foods. He explains the rigorous process of reviewing scientific literature, the challenges in translating research into policy, and the critical role of health equity in shaping the recommendations. By exploring these themes, this episode aims to provide clarity on the scientific foundation behind the upcoming dietary guidelines. Whether you’re a nutrition professional, researcher, or someone interested in how dietary recommendations are formed, this conversation sheds light on the key discussions shaping the future of nutrition policy. Timestamps [03:38] Interview begins [07:18] The rigorous process behind formulating dietary guidelines [12:10] Key questions addressed and major findings from the report [25:41] Identifying nutrients of concern and refining dietary patterns [33:39] The importance of health equity in dietary recommendations [36:04] Reassessing dairy’s role in different population groups [41:05] Shifting the focus towards plant-based protein sources [47:52] The debate on ultra-processed foods and public health implications [58:24] Key Ideas segment (Premium-only) Related Resources Enroll in the next cohort of our Applied Nutrition Literacy course Subscribe to Sigma Nutrition Premium Join the Sigma email newsletter for free Scientific Report of the 2025 Dietary Guidelines Advisory Committee Previous episode with Prof. Gardner: Episode 223…
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Sigma Nutrition Radio


1 #554: Crucial Ideas for Understanding Nutrition Science 1:13:12
1:13:12
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Understanding the complexities of diet-disease relationships requires a nuanced approach to nutritional science. Unlike other scientific disciplines, nutrition research often grapples with the inherent challenges of studying dietary patterns and nutrient intakes in free-living populations over long periods. The cumulative effects of dietary exposures, combined with the necessity to control for confounding factors such as total energy intake and population-specific dietary habits, highlight the need for rigorous study designs and careful interpretation of findings. Despite their utility, these methods are often misunderstood or misrepresented in public discourse. Addressing these misunderstandings requires a clear communication of key principles underpinning nutritional science, including the role of cumulative exposure, the importance of contextualizing absolute and relative risks, and the necessity of evaluating the long-term effects of dietary patterns. This episode aims to provide a comprehensive overview of these essential ideas, equipping readers with the tools to critically appraise the evidence and engage meaningfully with the ongoing conversation around nutrition research. Timestamps [03:26] Understanding nutrition science: core concepts [06:01] Standards of proof in nutrition research [19:39] Unique challenges in nutrition research [26:30] High vs. low exposure in nutrition studies [34:34] Challenges in nutrition randomized control trials [39:29] Understanding null by design in nutrition trials [41:58] The importance of temporal relationships in diet and disease [43:55] Relative risk vs. absolute risk [57:16] The role of substitution and adjustment in nutrition studies Related Resources Enroll in the next cohort of our Applied Nutrition Literacy course Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Episodes referenced: 531: Correlation, Causation & Cliché 478: Exposures in Nutrition – Why They’re Crucial to Understand 511: Null By Design – When “No Effect” Doesn’t Mean No Effect 378: Nutritional Epidemiology 472: Compared To What? – Understanding Food Substitution Analysis & Adjustment Models…
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Sigma Nutrition Radio


This episode focuses on the intersection of nutrition, lifestyle, and women’s health, with a particular emphasis on managing complex conditions such as PCOS, endometriosis, and premenstrual dysphoric disorder (PMDD). Registered dietitian Marjorie Nolan Cohn shares insights from over two decades of clinical practice, highlighting the importance of addressing foundational health behaviors—such as adequate sleep, hydration, and nutrient-dense dietary patterns—before introducing targeted interventions like supplementation. Marjorie explores the nuanced relationship between body weight, metabolic health, and fertility, while addressing misconceptions around weight loss as a primary health goal. The episode examines the role of long-term, individualized care in improving symptoms and outcomes for women experiencing significant menstrual-related challenges. Practical considerations for practitioners, including strategies to build trust, identify key barriers, and provide holistic support, are outlined alongside the importance of interdisciplinary collaboration to improve care quality. Marjorie Nolan Cohn is a registered dietitian with a Masters Degree in Food and Nutrition Science from the Indiana University of Pennsylvania. She is the Clinical Director of Berry Street, a company providing virtual in-network nutritional counseling to people across the US. Timestamps [04:32] Beginning of the interview [08:39] The role of nutrition in fertility [13:40] Understanding PCOS and endometriosis [16:28] Barriers to accurate women’s health diagnoses [19:03] Exploring diet and lifestyle strategies [23:28] Addressing challenges in women’s health and nutrition [39:01] Closing remarks and final takeaways Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Guest website: Berry Street…
Over the past couple of decades, renowned researcher Dr. Marie-Pierre St-Onge has uncovered fascinating links between how we sleep and what we eat, revealing how these two lifestyle factors influence energy balance, cardiovascular health, and metabolic function. In this episode we’ll explore Dr. St-Onge’s findings on sleep regularity and its association with reduced mortality risk, providing actionable insights for optimizing your lifestyle. With a focus on combining rigorous methodologies and controlled dietary interventions, her research sheds light on the complex mechanisms connecting sleep, diet, and metabolic health. Timestamps: [03:39] Dr. St-onge's academic journey and evolution of her research interests [07:03] Overcoming methodological challenges in sleep and nutrition research [10:20] The importance of sleep regularity for health [15:44] Exploring the bidirectional connection between diet and sleep [23:40] Unpacking the mechanisms linking diet to sleep quality [37:33] Practical recommendations for optimizing sleep and diet Links: Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Article: How Sleep & Nutrition Interact – Alan Flanagan, PhD Go to episode page…
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Sigma Nutrition Radio


Multivitamin and multimineral supplements have long been a topic of both scientific inquiry and public debate. While they are often marketed as convenient solutions for achieving nutritional adequacy, their true value remains contentious. Are these supplements essential insurance policies against nutrient deficiencies, or are they merely expensive placebos? Importantly, how should we weigh their potential benefits against the lack of robust evidence for long-term health outcomes such as reduced mortality or chronic disease risk? These questions demand a nuanced exploration, grounded in the context of specific populations and individual needs. Ultimately, the role of multivitamin supplements cannot be assessed in isolation but must be viewed through the lens of context and specificity. How do we balance the biological plausibility of benefits against the variability of individual diets, the presence of fortification policies, and the challenges of achieving dietary adequacy in certain life stages? These considerations invite a more thoughtful and less binary discussion about whether, when, and for whom multivitamins are a worthwhile addition to the diet. Timestamps [00:22] The debate on multivitamins: worthless or beneficial? [00:53] Rationale behind multivitamin use [04:04] Modern nutritional adequacy and multivitamins [07:10] Evidence supporting multivitamin use [23:39] Long-term health outcomes and multivitamins [41:43] Cognitive outcomes [50:18] Pregnancy and multivitamin use Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Shaun Ward Article: Multivitamin Madness: There’s More to Life than Death Studies mentioned: MacPherson et al., 2013 meta-analysis of randomized controlled trials Jenkins et al., 2021 meta-analysis COSMOS trial – Vyas et al., 2024 analysis of three substudies Loftfield et al., 2024 – Multivitamin Use and Mortality in 3 Cohorts Blumberg et al., 2017 nutritional adequacy paper…
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Sigma Nutrition Radio


1 #551: How to Shift from Short-term Dieting to Sustainable Lifestyle Changes – Laurin Conlin 1:02:19
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دوست داشته شد1:02:19
While the fitness industry often emphasizes short-term goals such as rapid weight loss or aesthetic improvements, a growing body of evidence highlights the importance of fostering long-term habits for health and wellbeing. Understanding how psychological frameworks intersect with physical health behaviors is key to empowering clients and overcoming the challenges posed by rigid dieting practices or the influence of social media culture. Bodybuilding and fitness culture serve as both a microcosm and an extreme example of the challenges faced in this space. As the boundaries between physique sports and general fitness blur, many enthusiasts adopt unsustainable habits without fully understanding their long-term implications. How can fitness professionals effectively guide clients toward intrinsic motivations and healthier relationships with food and exercise while balancing the reality of external pressures? In this episode, Laurin Conlin offers her insights based on her coaching experiences, as well as formal training in exercise sciences and mental health counselling. Dr. Eric Trexler co-hosts the episode with Danny Lennon. Timestamps [05:41] Challenges in dieting and coaching practices [09:58] Bridging physical and mental health through coaching practices [13:15] Recognizing and navigating disordered eating behaviors in fitness clients. [22:01] The physiological and psychological challenges in physique sports. [34:52] Fitness culture and social media influence [37:19] Misunderstanding intuitive eating [41:23] Using motivational interviewing and reflective listening to guide clients [52:13] Integrating mental health practices in fitness and nutrition coaching [62:13] Key Ideas segment (Premium-only) Related Resources Go to episode page Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Sports Nutrition Association Get research reviews from Dr. Eric Trexler and collegues…
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Sigma Nutrition Radio


Eating disorders and disordered eating behaviors represent complex, multifaceted challenges that affect individuals across all demographics, yet they remain widely misunderstood and under-recognized. These issues often extend beyond the stereotypical images associated with eating disorders, touching everything from rigid “clean eating” obsessions to the normalized extremes of diet culture. At the heart of these behaviors lies a disruption in one’s relationship with food, often fueled by societal pressures, unrealistic body ideals, and a pervasive focus on aesthetics over health. While these challenges are tenacious, recovery and improved relationships with food are possible with the right interventions, resources, and awareness. In this episode, Danny talks to Dr. Jillian Lampert, a registered dietitian with a PhD in public health nutrition, with a speciality in eating disorders and disordered eating. Timestamps [02:56] – What are eating disorders? a breakdown of core concepts [05:15] – Beyond stereotypes: the widespread impact of eating disorders [14:41] – Disordered eating in sports and fitness: risks and realities [19:41] – Guidance for practitioners: recognizing and addressing red flags [22:50] – Barriers in treating eating disorders: challenges and solutions [43:50] – Advocacy and systemic change: the future of eating disorder care Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Go to episode page The Emily Program Eating Disorders Coalition for Research, Policy, & Action (EDC) National Alliance for Eating Disorders…
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Sigma Nutrition Radio


1 #549: Are We Doomed? Trust, Misinformation, and the Future of Health & Fitness Science – Joe Klemczewski, PhD 1:19:25
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دوست داشته شد1:19:25
In a world flooded with information, discerning fact from fiction in fitness and nutrition has never been more challenging—or more important. The rise of social media and democratized science has given everyone a platform, but not all voices are equal. How do we navigate a landscape where influencers with massive followings wield the same credibility as seasoned experts? Why do pseudoscientific trends gain traction while nuanced evidence gets lost in the noise? In this episode we also dive into the evolution of coaching, examining how the obsession with quantifiable metrics has shifted the focus away from human connection. How can professionals balance the drive for scalable success with the need for meaningful client relationships? And what lessons can we draw from decades of shifts in the fitness industry to stay resilient amid rapid societal and technological changes? Timestamps [04:33] Eric’s personal journey and influence [06:08] Evolution of bodybuilding coaching [10:32] Challenges in interpreting scientific research [17:35] Historical trends in diet and nutrition [25:49] Information overload and misinformation [43:07] Understanding fractional counting in hypertrophy [44:24] Challenges in communicating scientific concepts [47:27] The psychology of persuasion [49:07] The role of marketing in science communication [54:46] Balancing data and intuition in coaching [01:03:59] Navigating the future of nutrition coaching [01:08:34] Building trust and connection with clients Related Resources Go to episode page Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Dr. Helms’ MASS Research Review is a monthly publication that includes easy-to-read breakdowns of the latest training and nutrition research…
IGF-1 (Insulin-Like Growth Factor 1) has emerged as a hot topic in health and nutrition discussions, often linked to longevity, cancer risk, and metabolic health. On one hand, IGF-1 is essential for growth, repair, and metabolic regulation; on the other, it is sometimes associated with disease processes, including cancer and cognitive decline. For those intrigued by the intersection of nutrition, biomarkers, and disease prevention, IGF-1 offers an opportunity to explore how science grapples with these complexities. Claims about manipulating IGF-1 through dietary changes — whether by reducing protein or adopting fasting protocols — are common. But does the evidence support these claims? If you’re curious about IGF-1 and the relationships between diet, disease, and healthy aging, in this Premium-exclusive episode Danny and Alan discuss this fascinating topic. To listen to the full episode, subscribe to Sigma Nutrition Premium Timestamps [02:21] IGF-1 and Diet: Examining the Relationship [09:15] IGF-1 as a Biomarker: Challenges with Sensitivity and Specificity [11:54] IGF-1 and Cancer Risk: Insights and Complexities [25:51] IGF-1 in Aging: Cognitive Function and Longevity Considerations [43:38] Key Takeaways: IGF-1, Diet, and Practical Advice Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Murphy et al., 2020 – observational and Mendelian randomization analyses…
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Sigma Nutrition Radio


Fitness pursuits can bring various benefits. However, within the modern fitness industry there is a complex interplay of body image ideals, societal pressures, and disordered eating behaviors. Research continues to illuminate how certain practices and messaging within the industry—such as the overvaluation of leanness or the impact of social media personas—can fuel body dissatisfaction and disordered eating. For fitness coaches and enthusiasts alike, this raises important questions: What defines success in fitness? How can individuals engage in training and nutrition without falling into harmful traps? And how can professionals align their practices with values that support long-term well-being for themselves and their clients? In this episode, Michelle Carroll, a PhD researcher in clinical psychology, explores these questions in depth. Drawing on her academic work and personal experiences, she discusses the implications of fitness industry norms, the challenges of online coaching, and practical steps for fostering healthier relationships with food and body image. Timestamps [01:15] Defining disordered eating and body image [03:47] Motivations behind this research [05:37] Impact of the fitness industry on body image [08:29] Challenges and misconceptions about body image [14:26] Physical capital and pressures on fitness professionals [18:20] Consequences of harmful fitness industry messaging [35:04] Positive changes and gaps for future research [40:16] Practical advice for professionals and individuals Related Resources Go to episode page Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Michelle’s website Michelle on Instagram: @michellecarroll1 Disordered Eating Informed – Course…
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Sigma Nutrition Radio


1 #547: Healthspan, Healthy Ageing & Chronic Disease – Best of 2024 1:06:18
1:06:18
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دوست داشته شد1:06:18
Healthspan, healthy ageing, and chronic disease are pivotal topics in today’s health discourse, emphasizing not just the length of life but the quality of those additional years. Focusing on healthspan means striving for a longer period of life free from disease and disability, which is increasingly important as global life expectancies rise. Healthy ageing involves adopting lifestyle habits that promote physical, mental, and social well-being throughout the lifespan, thereby reducing the risk of chronic diseases such as heart disease, diabetes, and neurodegenerative disorders. Addressing chronic diseases risk requires a proactive approach centered on prevention and early intervention. By prioritizing healthspan and healthy ageing, individuals can significantly decrease the likelihood of developing chronic illnesses, leading to improved quality of life and reduced healthcare costs. Sigma Nutrition Radio has consistently addressed these critical themes across many episodes. In this episode, we go back over some of the best episodes of 2024 in this area, including discussions on Alzheimer’s, cholesterol-lowering medications, impact of exercise, and the debate about red meat. Timestamps (03.12) Alzheimer’s: Genetic susceptibility vs. modifiable factors (14.59) Heart disease: the “risk factor, disease, event” framework (22.10) The strength of evidence we have for the impact of exercise on mortality and longevity (28.23) Why high blood pressure is so problematic (37.23) Where do we see risk for unprocessed red meat? (48.34) The evolution over the years of dietary fat research (53.20) Claims about the proposed risks of consuming seed oils (56.16) How does fat quality impact heart disease risk? (60.35) History of Portfolio Diet research for reducing LDL-C Episodes referenced: 512: Alzheimer’s Disease – Drs. Ayesha & Dean Sherzai 525: Cholesterol-Lowering Medication – Dr. Paddy Barrett 524: Strength & Fitness Levels for Reducing Chronic Disease Risk & Promoting Health Ageing – Jordan Feigenbaum, MD 527: How to Prevent & Treat Hypertension – Dr. Mohammed Alo, DO 528: Is Unprocessed Red Meat Problematic for Our Health? 532: Dietary Fat: Evidence vs. Misinformation – Alice Lichtenstein, DSc 515: Does Dietary Fat Quality Causally Affect Atherosclerosis Risk? – Jacob Christensen, PhD 507: Does a Higher Portfolio Diet Score Reduce Heart Disease? – Andrea Glenn, PhD Links: Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Go to episode page…
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Sigma Nutrition Radio


Navigating the complex and often underemphasized requirements of professional standards, legal considerations, and insurance can be challenging for sports nutrition practitioners and personal trainers. Many professionals, especially early in their careers, may overlook or minimize these responsibilities, focusing primarily on the practical and enjoyable aspects of helping clients achieve their goals. However, staying informed and adhering to these standards is not only essential for providing ethical, competent service but is also crucial for minimizing liability. Ignoring or misinterpreting scope-of-practice guidelines and insurance limitations can leave well-meaning professionals exposed to significant legal and financial risks that could have lasting consequences on their careers. In this episode, Alex Thomas joins Danny Lennon and Eric Helms to discuss the essential, if often overlooked, responsibilities that define a successful and resilient career in sports nutrition. Together, they explore best practices for insurance, scope of practice, and the importance of aligning with professional organizations that provide educational and legal support. Timestamps [01:57] The SNA Introduction [03:31] The importance of professional standards [09:58] Legal consequences and real-world examples [15:23] Insurance and scope of practice [23:27] Navigating the gray areas in nutrition practice [30:51] Legal risks in nutrition advice [34:50] Ethical dilemmas and referral networks [36:53] Emerging trends and risks in nutrition services [48:49] Becoming a competent sports nutrition professional Links Go to episode page Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Sports Nutrition Association…
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Carbohydrate metabolism and metabolic health have become central themes in the science of nutrition, with questions about fuel utilization, the impact of different diets, and the potential of ketone supplements driving new research. As researchers continue to uncover how the body adapts to various energy sources, there are emerging insights into how glucose tolerance, glycogen utilization, and even ketogenic diets influence not only physical performance but also long-term health outcomes. Understanding how the body responds to different energy sources, particularly in relation to carbohydrate restriction, brings crucial context to popular nutrition strategies and the potential benefits—or trade-offs—they offer. In this episode, Professor Javier Gonzalez joins to discuss these topics in detail, exploring the latest findings on how dietary choices affect athletic performance, chronic disease risk, and the mechanisms underlying metabolic adaptations. You will gain insight into topics like reactive hypoglycemia, carbohydrate oxidation, and why individualized responses to diet matter. Timestamps [01:36] Understanding carbohydrate metabolism [06:33] The role of glucose in metabolic health [09:59] Exercise and glucose dynamics [17:35] Carbohydrate intake and athletic performance [25:03] Diet impact on exercise and metabolism [30:44] Pre-workout carbohydrates and reactive hypoglycemia [35:31] Recent study: Ketogenic diet vs. sugar restriction [41:09] Future research directions in metabolic health [45:07] Ketone esters and their role in exercise performance [49:22] Carbohydrate metabolism and common misconceptions Links Go to episode page Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Paper: Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT…
Appetite and satiety are fundamental concepts shaping how we eat, why we feel hunger, and what keeps us satisfied after meals. From the biological signals sent by our gut to the psychological influences of food cues, understanding these processes can provide valuable insights into how we manage our food intake. In this episode, we delve into the interplay between hormones, food properties, and external factors that regulate appetite and fullness, exploring how these mechanisms work together—or sometimes fail—in modern eating environments. We will examine fascinating topics such as the satiety cascade, sensory-specific satiety, and the impact of nutrient composition on hunger regulation. This episode also highlights how individual differences, such as satiety phenotypes, shape eating behavior, offering a nuanced perspective on the science of satiety. Whether you’re interested in applying these concepts to your diet or supporting others in managing hunger, this discussion offers practical takeaways grounded in scientific evidence. To listen to the full episode, subscribe to Sigma Nutrition Premium . Timestamps [02:22] Understanding appetite and satiety [07:28] Biological mechanisms behind hunger regulation [10:57] Sensory and psychological cues affecting food intake [26:54] Nutrient composition and its influence on satiety [43:11] Practical strategies for managing hunger Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course…
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Sigma Nutrition Radio


In the realm of nutrition science, individual differences are more profound and impactful than many realize. For decades, we’ve developed dietary recommendations with a “one-size-fits-all” approach, assuming that most people respond similarly to specific nutrients. But Dr. Martin Kohlmeier, a pioneer in precision nutrition, challenges this very notion. How might an individual’s genetic makeup alter their need for certain nutrients? With advances in nutrigenetics, we’re beginning to see how personalized nutrition could bridge long-standing gaps in dietary efficacy. Dr. Kohlmeier’s work highlights fascinating examples, from the APOE4 gene’s influence on cholesterol metabolism to variations in folate metabolism that could affect everything from heart health to birth outcomes. As Dr. Kohlmeier explains, precision nutrition is not simply about adding genetic testing to a wellness regimen. Instead, it requires rethinking nutrition research from the ground up—ensuring studies capture these individual variations and that public health policy moves beyond broad averages. With genetic testing now more accessible than ever, could commercial pressures and oversimplified testing derail the science before it even gets going? In this episode, we dive deep into the potential and pitfalls of precision nutrition, exploring the future of personalized dietary advice and the road to truly individualized health. Timestamps [02:33] Introduction of Dr. Martin Kohlmeier and his background [05:10] Rethinking assumptions in nutrition science [07:42] The role of genetic variations in nutrient responses [13:15] Practical examples of genetic impact on nutrition [22:55] Misinformation and commercial misuse in nutrigenetics [29:48] Case studies: cholesterol sensitivity (APOE4) and folate metabolism (MTHFR) [41:03] Public health implications and the need for tailored research [49:27] Future directions and the path forward for precision nutrition Links Go to episode page Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Kohlmeier, 2023 – One size does not fit all: on the need for categorical stratification in nutrition science, practice and policy…
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