Artwork

محتوای ارائه شده توسط Peter Attia, MD, Peter Attia, and MD. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Peter Attia, MD, Peter Attia, and MD یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
Player FM - برنامه پادکست
با برنامه Player FM !

#236 ‒ Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D.

1:56:43
 
اشتراک گذاری
 

Manage episode 351312213 series 2394217
محتوای ارائه شده توسط Peter Attia, MD, Peter Attia, and MD. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Peter Attia, MD, Peter Attia, and MD یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

View the Show Notes Page for This Episode

Become a Member to Receive Exclusive Content

Sign Up to Receive Peter’s Weekly Newsletter

Kellyann Niotis is a neurologist specializing in risk reduction strategies for the prevention or slowing of neurodegenerative disorders. In this episode, Kellyann provides an overview of the various diseases associated with neurodegeneration, including, but not limited to, Alzheimer’s disease, Lewy body dementia, and Parkinson’s disease. She goes in-depth on Parkinson’s disease, explaining its pathology, role in movement capacity, very early warning signs, and the role of anxiety and sleep. Similarly, she provides an in-depth discussion of Alzheimer’s disease, including the latest in screening, genetics, and tools/strategies for prevention. She ties the discussion together by explaining the differences and commonalities among the various diseases of neurodegeneration and the potential causative triggers, and she highlights the importance of early screening, cognitive testing, and taking the proper steps to lowering the risk of disease.

We discuss:

  • Kellyann’s background, training, and interest in the brain [2:30];
  • A primer on neurodegeneration: different types, prevalences, interventions, and more [5:30];
  • Overview of Parkinson’s disease and neuromuscular disorders including ALS [16:00];
  • Parkinson’s disease: early signs, diagnosis, genetics, causative triggers, and more [17:30];
  • Interventions to delay or avoid Parkinson’s disease, and the role of sleep and anxiety [31:15];
  • The challenge of standardizing early interventions for Parkinson’s disease without a clear biomarker [39:45];
  • Alzheimer’s disease: pathophysiology and the role of the amyloid and tau proteins [47:45];
  • Can PET scans be informative for diagnosing Alzheimer’s disease? [51:15];
  • Tau accumulation in the brain, tau scans, serum biomarkers, and possible early detection of Alzheimer’s disease pathology [57:00];
  • Cognitive testing explained [1:03:30];
  • The challenge of identifying the stage of the disease and why drugs have not shown efficacy [1:14:45];
  • The association between hearing loss and dementia [1:17:45];
  • The relationship between oral health and neurodegenerative diseases [1:21:30];
  • Genetic risk for Alzheimer’s disease [1:24:45];
  • What one’s mitochondrial haplotype can reveal about their risk of neurodegenerative disease [1:32:30];
  • The positive impact of exercise on brain health [1:37:00];
  • High blood pressure as a risk factor [1:40:00];
  • Why women are disproportionately affected by Alzheimer’s disease [1:44:15];
  • Final takeaways: the future of understanding neurodegenerative disease and further reducing risk [1:46:45]; and
  • More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

  continue reading

346 قسمت

Artwork
iconاشتراک گذاری
 
Manage episode 351312213 series 2394217
محتوای ارائه شده توسط Peter Attia, MD, Peter Attia, and MD. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Peter Attia, MD, Peter Attia, and MD یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

View the Show Notes Page for This Episode

Become a Member to Receive Exclusive Content

Sign Up to Receive Peter’s Weekly Newsletter

Kellyann Niotis is a neurologist specializing in risk reduction strategies for the prevention or slowing of neurodegenerative disorders. In this episode, Kellyann provides an overview of the various diseases associated with neurodegeneration, including, but not limited to, Alzheimer’s disease, Lewy body dementia, and Parkinson’s disease. She goes in-depth on Parkinson’s disease, explaining its pathology, role in movement capacity, very early warning signs, and the role of anxiety and sleep. Similarly, she provides an in-depth discussion of Alzheimer’s disease, including the latest in screening, genetics, and tools/strategies for prevention. She ties the discussion together by explaining the differences and commonalities among the various diseases of neurodegeneration and the potential causative triggers, and she highlights the importance of early screening, cognitive testing, and taking the proper steps to lowering the risk of disease.

We discuss:

  • Kellyann’s background, training, and interest in the brain [2:30];
  • A primer on neurodegeneration: different types, prevalences, interventions, and more [5:30];
  • Overview of Parkinson’s disease and neuromuscular disorders including ALS [16:00];
  • Parkinson’s disease: early signs, diagnosis, genetics, causative triggers, and more [17:30];
  • Interventions to delay or avoid Parkinson’s disease, and the role of sleep and anxiety [31:15];
  • The challenge of standardizing early interventions for Parkinson’s disease without a clear biomarker [39:45];
  • Alzheimer’s disease: pathophysiology and the role of the amyloid and tau proteins [47:45];
  • Can PET scans be informative for diagnosing Alzheimer’s disease? [51:15];
  • Tau accumulation in the brain, tau scans, serum biomarkers, and possible early detection of Alzheimer’s disease pathology [57:00];
  • Cognitive testing explained [1:03:30];
  • The challenge of identifying the stage of the disease and why drugs have not shown efficacy [1:14:45];
  • The association between hearing loss and dementia [1:17:45];
  • The relationship between oral health and neurodegenerative diseases [1:21:30];
  • Genetic risk for Alzheimer’s disease [1:24:45];
  • What one’s mitochondrial haplotype can reveal about their risk of neurodegenerative disease [1:32:30];
  • The positive impact of exercise on brain health [1:37:00];
  • High blood pressure as a risk factor [1:40:00];
  • Why women are disproportionately affected by Alzheimer’s disease [1:44:15];
  • Final takeaways: the future of understanding neurodegenerative disease and further reducing risk [1:46:45]; and
  • More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

  continue reading

346 قسمت

همه قسمت ها

×
 
Loading …

به Player FM خوش آمدید!

Player FM در سراسر وب را برای یافتن پادکست های با کیفیت اسکن می کند تا همین الان لذت ببرید. این بهترین برنامه ی پادکست است که در اندروید، آیفون و وب کار می کند. ثبت نام کنید تا اشتراک های شما در بین دستگاه های مختلف همگام سازی شود.

 

راهنمای مرجع سریع