A very NACCT Holiday-2023 North American Congress of Clinical Toxicology High Yield Abstract Review

The Poison Lab

In this episode Ryan is joined by a guest panel (Dr. Grant Comstock MD, Dr. Joshua Trebach MD, Dr. Emily Kiernan DO, and Dr Frank Paloucek PharmD, DABAT) to review nine of the most interesting or clinically impactful research abstracts that were presented at the 2023 North American Congress of Clinical Toxicology (NACCT) in Montreal Canada. If you didn't get a chance to read all 363 research abstracts from some of Toxicology's best and brightest this year, tune in for a high yield review as well as clinical a break down of the studies and their relevance from the expert panel.

Check the show notes for a link to the published abstracts and the list of all studies discussed in the show

Abstracts available here

• 10:40- Abstract 1 (PDF #225) Methotrexate toxicity in the setting of therapeutic error, a multicenter retrospective review
  • Lead author: Andrew Chambers
• 24:12- Abstract #2 (PDF #251) Oleander seeds in candlenut weight loss product strike again
  • Lead author: Masha Yemets
• 31:16- Abstract #3 (PDF #2) Efficacy of sodium tetrathionate when administered intramuscularly for the treatment of acute oral cyanide toxicity in a swine model (Sus scrofa)
  • Lead author: Brooke Lajeunesse
• 39:45- Abstract #4 (PDF #10) Is HOUR enough after out-of hospital naloxone for opioid overdose? Prospective preliminary data from real-world implementation of the modified St. Paul’s early discharge rule
  • Lead author: Stephen Douglas
• 49:05- Abstract #5- Poster titles at NACCT 2013–2022: is NACCT experiencing a pun-demic?
  • Lead author: Dayne Laskey
• 52:40- Rivastigmine discussion
  • Lead author: none
• 58:40- Abstract #6 (PDF #5) Randomized controlled trial of ANEB-001 as an antidote for acute cannabinoid intoxication in healthy adults
  • Lead author: Andrew Monte
• 1:08:00- Abstract #7 (PDF#216) Successful use of expired physostigmine to treat anticholinergic delirium in a pediatric patient
  • Lead author: Bryan Hayes
• 01:20:00- Abstract #8 (PDF #202) Enough negativity? Clinically significant salicylism with first detectable concentration twelve hours )post-ingestion
  • Lead author: Stacey Bangh
• 01:25:24 - Abstract #9 (PDF #267) High sensitivity troponin is frequently elevated after carbon monoxide exposure
  • Lead author: Abdullatif Aloumi