Stress and the Prefrontal Cortex: An Interview with Dr. Amy Arnsten

Yale Journal of Biology and Medicine

How does stress affect the prefrontal cortex? In this episode of the YJBM podcast, host Delyar Khosroabadi speaks with Dr. Amy Arnsten, Albert E. Kent Professor of Neuroscience and Professor of Psychology. Dr. Arnsten shares the experience that sparked her interest in neuroscience, her journey as an undergraduate creating the first neuroscience major at Brown University, and what drew her to study the prefrontal cortex. She discusses dynamic network connectivity, the mechanism of action of guanfacine, and why prefrontal deficits begin to appear in middle age. Dr. Arnsten also offers fascinating insights on how exercise and a healthy diet can benefit the prefrontal cortex. Get to know YJBM at: https://medicine.yale.edu/yjbm/ Integrative Medicine issue: https://www.ncbi.nlm.nih.gov/pmc/issues/471502/ Our Instagram: https://www.instagram.com/theyjbm/