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محتوای ارائه شده توسط BEaTS Research Radio. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط BEaTS Research Radio یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
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Building Barriers: Replicating the Brain's Shield

15:19
 
اشتراک گذاری
 

Manage episode 454034741 series 2849626
محتوای ارائه شده توسط BEaTS Research Radio. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط BEaTS Research Radio یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

Maryam Yassin from the University of Ottawa interviews Dr. Anna Jezierski and Dr. Alex MacKenzie. Dr. Jezierski is a research officer at the Department of Translational Biosciences in the Human Health Therapeutics Research Center at the National Research Council of Canada. She is also an adjunct professor for the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. In this episode, Dr. Jezierski shares her research on modeling the human blood-brain barrier using induced pluripotent stem cells and the various applications of this model in studying therapeutics for diseases of the central nervous system. We're also joined by Dr. Alex Mackenzie, an attending pediatrician and senior scientist at the Children's Hospital of Eastern Ontario (CHEO). He has served as the CEO and Scientific Director of CHEO Research Institute and is a cross-appointed member of the Faculty of Medicine at the University of Ottawa. Dr. Mackenzie comments on how this model is revolutionizing drug development.
Learn more: https://www.uottawa.ca/faculty-medicine/dr-anna-jezierski
https://www.cheoresearch.ca/research/find-a-researcher/alex-mackenzie/
0.03 | BEaTS and host introduction.
0.26 | Introduction to Dr. Jezierski.
1.17 | Introduction to Blood-Brain Barrier (BBB).
3.22 | Creating a BBB model using induced pluripotent stem cells is important.
7.07 | How tight junctions are replicated effectively.
9.20 | Applications of the iPSC-derived BBB model.
12.35 | Introduction to Dr. Alex Mackenzie
12.51 | Implications of the model on drug discovery and clinical trials.
14.54 | Closing remarks.
Soundtracks by the Underground Drive. All rights reserved. Listen more
https://www.dropbox.com/scl/fo/yrgjajtxzy4j08zj5iptc/AF7HMueoQwogLQMFxHxSHpU?e=1&preview=BEaTS+-+music+only+2.wav&rlkey=epcpj63eohwgi44mnqg7ctoa6&st=bn1v69ik&dl=0
Maryam Yassin (Voice), Aysha Aftab (Post-Production), Dalia Zeidan (Content Generation), Jordan Yin (Producer).

  continue reading

فصل ها

1. Building Barriers: Replicating the Brain's Shield (00:00:00)

2. BEaTS and host introduction (00:00:03)

3. Introduction to Dr. Jezierski (00:00:26)

4. Introduction to Blood-Brain Barrier (BBB) (00:01:17)

5. Creating a BBB model using induced pluripotent stem cells is important (00:03:22)

6. How tight junctions are replicated effectively (00:07:07)

7. Applications of the iPSC-derived BBB model (00:09:20)

8. Introduction to Dr. Alex Mackenzie (00:12:35)

9. Implications of the model on drug discovery and clinical trials (00:12:51)

31 قسمت

Artwork
iconاشتراک گذاری
 
Manage episode 454034741 series 2849626
محتوای ارائه شده توسط BEaTS Research Radio. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط BEaTS Research Radio یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

Maryam Yassin from the University of Ottawa interviews Dr. Anna Jezierski and Dr. Alex MacKenzie. Dr. Jezierski is a research officer at the Department of Translational Biosciences in the Human Health Therapeutics Research Center at the National Research Council of Canada. She is also an adjunct professor for the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. In this episode, Dr. Jezierski shares her research on modeling the human blood-brain barrier using induced pluripotent stem cells and the various applications of this model in studying therapeutics for diseases of the central nervous system. We're also joined by Dr. Alex Mackenzie, an attending pediatrician and senior scientist at the Children's Hospital of Eastern Ontario (CHEO). He has served as the CEO and Scientific Director of CHEO Research Institute and is a cross-appointed member of the Faculty of Medicine at the University of Ottawa. Dr. Mackenzie comments on how this model is revolutionizing drug development.
Learn more: https://www.uottawa.ca/faculty-medicine/dr-anna-jezierski
https://www.cheoresearch.ca/research/find-a-researcher/alex-mackenzie/
0.03 | BEaTS and host introduction.
0.26 | Introduction to Dr. Jezierski.
1.17 | Introduction to Blood-Brain Barrier (BBB).
3.22 | Creating a BBB model using induced pluripotent stem cells is important.
7.07 | How tight junctions are replicated effectively.
9.20 | Applications of the iPSC-derived BBB model.
12.35 | Introduction to Dr. Alex Mackenzie
12.51 | Implications of the model on drug discovery and clinical trials.
14.54 | Closing remarks.
Soundtracks by the Underground Drive. All rights reserved. Listen more
https://www.dropbox.com/scl/fo/yrgjajtxzy4j08zj5iptc/AF7HMueoQwogLQMFxHxSHpU?e=1&preview=BEaTS+-+music+only+2.wav&rlkey=epcpj63eohwgi44mnqg7ctoa6&st=bn1v69ik&dl=0
Maryam Yassin (Voice), Aysha Aftab (Post-Production), Dalia Zeidan (Content Generation), Jordan Yin (Producer).

  continue reading

فصل ها

1. Building Barriers: Replicating the Brain's Shield (00:00:00)

2. BEaTS and host introduction (00:00:03)

3. Introduction to Dr. Jezierski (00:00:26)

4. Introduction to Blood-Brain Barrier (BBB) (00:01:17)

5. Creating a BBB model using induced pluripotent stem cells is important (00:03:22)

6. How tight junctions are replicated effectively (00:07:07)

7. Applications of the iPSC-derived BBB model (00:09:20)

8. Introduction to Dr. Alex Mackenzie (00:12:35)

9. Implications of the model on drug discovery and clinical trials (00:12:51)

31 قسمت

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