Healthy Calves Now Prevents BRD

Ranch It Up Radio Show & Podcast

We discuss getting and keeping this year's calf crop healthy. Plus, updates on Beef imports and exports, new possible genetic defects, markets, recaps, sales and more on this all new episode of the Ranch It Up Radio Show. Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel.

EPISODE 189 DETAILS BOVINE RESPIRATORY DISEASE (BRD), MANAGE IT NOW. OVERVIEW OF BOVINE RESPIRATORY DISEASE COMPLEX

Bovine respiratory disease (BRD), shipping fever pneumonia, or undifferentiated fever is a respiratory disease of cattle of multifactorial etiology with Mannheimia haemolytica and, less commonly, Pasteurella multocida, Histophilus somni ( see Histophilosis), or Mycoplasma bovis being the important bacterial agents involved. Viral pathogens may also be involved, such as bovine herpesvirus 1, parainfluenza-3 virus, and bovine respiratory syncytial virus.

BRD has a multifactorial etiology and develops as a result of complex interactions between environmental factors, host factors, and pathogens. Environmental factors (eg, weaning, transport, commingling, crowding, inclement weather, dust, and inadequate ventilation) serve as stressors that adversely affect the immune and nonimmune defense mechanisms of the host animal. In addition, certain environmental factors (eg, crowding and inadequate ventilation) can enhance the transmission of infectious agents among animals. Many infectious agents have been associated with BRD. An initial pathogen (eg, a virus) may alter the animal’s defense mechanisms, allowing colonization of the lower respiratory tract by bacteria.

BRD is most commonly associated with the transport and assembly of large groups of recently weaned calves into feedlots. Morbidity in these types of feeder calves often peaks within the first 7–10 days after feedlot arrival. Morbidity can approach 35%–50%, and case fatality is 5%–10%; however, the levels of morbidity and mortality strongly depend on the array of risk factors present in the cattle being fed. The use of broad-spectrum antimicrobials labeled for bovine respiratory disease is the primary treatment, with macrolides and fenicols most commonly used as first-line treatment. Prevention and control are achieved via vaccination programs, preconditioning, identification and treatment of subclinically infected animals, and biosecurity.

Etiology of Bovine Respiratory Disease

The pathogenesis of bovine respiratory disease involves a stress factor, sometimes coupled with viral infection, which results in suppressed immune defenses and the proliferation of bacteria in the upper respiratory tract. Subsequently, these bacteria colonize the lower respiratory tract and cause bronchopneumonia with a cranioventral distribution in the lung. Many of the bacteria and viruses involved are commensal organisms of the upper respiratory tract that can be isolated from a proportion of healthy animals.

Multiple stress factors contribute to the suppression of host defense mechanisms in cattle. Weaning is a noteworthy stressor, and the incidence of this disease is highest in recently weaned calves. Transportation over long distances serves as a stressor; it may be associated with exhaustion, starvation, dehydration, chilling, and overheating, depending on weather conditions. Additional important stressors include passage through auction markets; commingling, processing, and surgical procedures on arrival at the feedlot; dusty environmental conditions; and nutritional stress associated with a change to high-energy rations in the feedlot. The individual viral and bacterial etiologies, clinical signs, lesions, and treatment are discussed under Viral Infections Associated with Bovine Respiratory Disease Complex in Cattle and Bacterial Pneumonia in Cattle with Bovine Respiratory Disease Complex.

Viruses associated with BRD include:

• bovine herpesvirus 1 (IBR)
• bovine respiratory syncytial virus
• parainfluenza-3 virus
• bovine viral diarrhea virus
• bovine adenovirus
• bovine coronavirus

Bacteria associated with BRD include:

• Mannheimia haemolytica
• Pasteurella multocida
• Histophilus somni
• Mycoplasma bovis
• Bibersteinia trehalosi

Control and Prevention of Bovine Respiratory Disease

Prevention of bovine respiratory disease should focus on decreasing the stressors that contribute to development of the disease. Cattle should be assembled rapidly into groups, and new animals should not be introduced to established groups. Mixing of cattle from different sources should be avoided or minimized if possible; however, in the North American beef industry, this risk factor is almost unavoidable for large intensive feedlots. Transport time should be minimized, and rest periods, with access to feed and water, should be provided during prolonged transport. Calves should ideally be weaned 2–3 weeks before shipment, and surgical procedures should be performed in advance of transport; however, the availability of these “preconditioned” calves is quite limited.

Cattle should receive arrival processing, which would include vaccinations and possibly metaphylactic antimicrobials within 48 hours after arrival at the feedlot. Adaptation to high-energy rations should be gradual, because acidosis, indigestion, and anorexia may inhibit the immune response. Vitamin and mineral deficiencies should be corrected. Dust control measures should be used.

Metaphylaxis with long-acting antimicrobials, such as oxytetracycline, tilmicosin, florfenicol, gamithromycin, tildipirosin, or tulathromycin, has been widely adopted as a control measure given “on arrival” to cattle at high risk of developing shipping fever pneumonia. Metaphylaxis on arrival has been shown to substantially decrease morbidity, improve rate of gain, and, in some cases, decrease mortality. Mass medication in feed or water is of limited value because sick animals do not eat or drink enough to achieve inhibitory blood levels of the antimicrobial, and many of these oral antimicrobials are poorly absorbed in ruminants.

On arrival, processing usually involves administration of modified live virus vaccines for viral antigens and for bacterial components of shipping fever pneumonia. Because most cases of pneumonia occur during the first 2 weeks after arrival, these on-arrival vaccines may not have adequate time to stimulate complete immunity in all individuals. When possible, vaccinations for the viral and bacterial components of shipping fever pneumonia should be given 2–3 weeks before transport or earlier and can be repeated on entry to the feedlot.

Key Points

• BRD is the most common and costly disease affecting the North American beef cattle industry.
• BRD risk factors include weaning, transportation, adverse weather, commingling, and stressful events such as dehorning and castration.
• BRD is caused by suppressed immune responses and initial viral infection, which allow colonization of the lung by commensal URT bacteria.
• Preconditioning, minimizing mixing, vaccination for BRD pathogens, and metaphylaxis for high-risk animals are major control methods.
• Broad-spectrum antimicrobials labeled for bovine respiratory disease are the primary treatment.

For More Information

• Key elements for implementing antimicrobial stewardship plans in bovine veterinary practices. American Association of Bovine Practitioners. Updated March 2022
• Joint AABP-AVC Judicious Therapeutic Use of Antimicrobials in Cattle

Cattle Industry News: Beef From Australia, New Genetic Defects, Alberta Prepares for HPAI, Trips Suspended to Michigan Farms U.S. IMPORTS OF AUSTRALIAN BEEF UP 74% FROM A YEAR AGO

Australian exports of beef to the United States have soared in the last 12 months, hitting over 31,000 tons in May. Compared to the same month a year ago, that sum is 74% higher, according to global supply analyst Tim Jackson of Meat & Livestock Australia, a checkoff group for the country’s red meat producers.

Australian farmers have also gained beef market share in Japan and South Korea largely at the expense of U.S. exporters, Jackson said. Australia’s global beef exports last month were up 9% from April and 25% from May 2023, hitting almost 114,000 tons — the highest level in more than four years. Jackson commented that the U.S. declines in production are now having a noticeable impact on export flows.

NEW GENETIC DEFECT AFFECTING CATTLE MOBIDITY AND MEAT QUALITY

Cattle have long been a cornerstone of agriculture, providing us with milk, meat, and various other products that nourish and sustain our communities. Ensuring the cattle’s health and optimal muscle development is vital when producing high-quality beef. However, various genetic conditions can disrupt muscle metabolism, affecting animals’ well-being and the quality of the meat they produce.

Researchers at the University of Nebraska — Lincoln have discovered a new defect in composite cattle (Simmental, Red Angus, Gelbvieh) that often caused physical collapse when they exercised, with some calves unable to recover. This is an autosomal recessive genetic defect, which means both parents of affected calves must carry one copy of the mutation.

TRIPS SUSPENDED TO MICHIGAN FARMS

The Michigan Department of Health and Human Services asked the public to postpone visits to farms with dairy herds and poultry flocks amid the HPAI outbreak. Over the past few weeks, Michigan has reported two human cases of the H5 virus. The department asked schools, daycares, camps and other programs to delay any planned field trips to farms.

ALBERTA PREPARES FOR HPAI IN CATTLE

According to Chris Scott with Meating Place dot com, Confirmation of H5 virus infections in U.S. dairy cows is prompting animal health officials in Canada to consider their options to prevent the virus from affecting herds north of the U.S. border.

Dr. Keith Lehman, Alberta’s chief veterinarian, told CBC News that vigilant surveillance is critical to protecting the Canadian dairy herd from a virus that has been confirmed among dairy cows in nine U.S. states so far. Canada imposed new import rules last month that require lactating cows from U.S. dairy farms test negative for H5 within seven days of export to help the nation maintain its HPAI-free status among cattle.

UPCOMING SALES & EVENTS

ISA Beefmasters: October 5, 2024, San Angelo, Texas

BULL SALE REPORT & RESULTS

Churchill Cattle Company

Van Newkirk Herefords

Gardiner Angus Ranch

Cow Camp Ranch

Jungels Shorthorn Farms

Ellingson Angus

Edgar Brothers Angus

Schaff Angus Valley

Prairie Hills Gelbvieh

Clear Springs Cattle Company

CK Cattle

Mrnak Hereford Ranch

Frey Angus Ranch

Hoffmann Angus Farms

Topp Herefords

River Creek Farms

Upstream Ranch

Gustin’s Diamond D Gelbvieh

Schiefelbein Farms

Wasem Red Angus

Raven Angus

Krebs Ranch

Yon Family Farms

Chestnut Angus

Eichacker Simmentals & JK Angus

Windy Creek Cattle Company

Pedersen Broken Heart Ranch

Mar Mac Farms

Warner Beef Genetics

Arda Farms & Freeway Angus

Leland Red Angus & Koester Red Angus

Fast - Dohrmann - Strommen

RBM Livestock

Weber Land & Cattle

Sundsbak Farms

Hidden Angus

Wheatland Cattle Company

Miller Angus Farms

L 83 Ranch

U2 Ranch

Vollmer Angus Ranch

A & B Cattle

Carter Angus Farms

Roller Ranch

Montgomery Ranch

Jorgensen Farms

DLCC Ranch

Four Hill Farm North Country Angus Alliance

Spruce Hill Ranch

Wilson Angus

FEATURING

Dave Sjeklocha, DVM

Merck Animal Health

@merckanimalhealth

https://www.merckvetmanual.com/

https://www.merck-animal-health-usa.com/

Mark VanZee

Livestock Market, Equine Market, Auction Time

https://www.auctiontime.com/

https://www.livestockmarket.com/

https://www.equinemarket.com/

@LivestockMkt

@EquineMkt

@AuctionTime

Kirk Donsbach: Stone X Financial

https://www.stonex.com/

@StoneXGroupInc

Shaye Koester

Casual Cattle Conversation

https://www.casualcattleconversations.com/

@cattleconvos

Questions & Concerns From The Field?

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References

https://www.stonex.com/

https://www.livestockmarket.com/

https://www.equinemarket.com/

https://www.auctiontime.com/

https://gelbvieh.org/

https://www.imogeneingredients.com/

https://alliedgeneticresources.com/

https://westwayfeed.com/

https://medoraboot.com/

http://www.gostockmens.com/

https://www.imiglobal.com/beef

https://www.tsln.com/

https://transova.com/

https://axiota.com/

https://www.merckvetmanual.com/respiratory-system/bovine-respiratory-disease-complex/overview-of-bovine-respiratory-disease-complex#Key-Points_v74932778

https://www.meatingplace.com/Industry/News/Details/114883

https://www.cattlebusinessweekly.com/articles/new-genetic-defect-impacting-cattle-morbidity-and-meat-quality/

https://www.meatingplace.com/Industry/News/Details/114869

https://www.meatingplace.com/Industry/News/Details/114841

https://www.merck-animal-health-usa.com/