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محتوای ارائه شده توسط Mito Health Coach Podcast and Mito Health Coach. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Mito Health Coach Podcast and Mito Health Coach یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
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Can nicotine increase mitochondrial function by reducing heteroplasmy?

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Manage episode 259263415 series 2654339
محتوای ارائه شده توسط Mito Health Coach Podcast and Mito Health Coach. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Mito Health Coach Podcast and Mito Health Coach یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
Products I've experimented with: Basic Care Nicotine Polacrilex Gum, 2 mg (nicotine), Original Flavor-https://amzn.to/2VQA2ln Pixotine Toothpicks (no additives)- https://pixotine.com/collections/nicotine-toothpicks ---------------------------------------------- Dr. Jack Kruse on nicotine 02.2.2016 (https://www.facebook.com/drjackkruse/posts/1150518161679203): Nicotine has dramatic effect on cytochrome 1 tunneling of electrons: What is that effect? It lowers the % heteroplasmy in mitochondria. Why? It pulses superoxide while shortening the respiratory complex path to stimulate mitophagy to get rid of shitty mitochondria using programs built into to it. If the mitochondria is really bad..........and nicotine won't work you might consider adding methylene blue and a large dash of sunlight to the RPE. FYI: This is a biohack from something I've written. Random thought of the week that should stun you: Half the bestselling drugs in the US target the product of a circadian gene yet pharma ignores chronobiology...........share it with your fellow MD's, family, friends and your patients. For example take the best selling drugs, the statins, do they target circadian cycles? Yep. How? They block the Q cycle moving electrons from cytochrome 1 to 3 to increase the distance electrons can tunnel. Every increase in one Angstroms slows tunneling speeds by a factor of ten. As tunneling speeds slow what occurs? Inflammation and swelling. What is inflammation at its fundamental level? It is the excess of protons and/or loss of electrons at your surfaces. The surfaces being the eye, gut, and skin. pH is a function of proton concentration; low pH = high proton concentration = inflammation = lower EZ in water. Water is a chromophore for red light in the solar spectrum. Once the EZ is formed by proteins filled with electrons touching water, the EZ grows massively when 270 nm UV light hits a surface. If you cannot build an EZ what kind of life do you get? Optimal or suboptimal? Do you think a device designed to deliver purple and red light using surface cooling might have an effect on performance since it acts on this fundamental mechanism? I bet many Quantlet beta testers are already writing down bio-hacks as they read this. The loss of an EZ around the mitochondria for any reason increases the distance between respiratory proteins at the atomic level measured by Angstroms too. DO you see how the link of statins and a loss of EZ are similar? Key take home repeatable point: for every increase of 1 Angstrom, the rate of quantum tunneling of electrons drops ten fold. Do you think that kind of redox drop has a small effect or no effect on bio-energenics in a cell? Or might this be exactly how heteroplasmy develops? Is this why statins cause cognitive delay and metabolic syndrome in tissues with high mitochondrial density? Statins are well known to increase the distance electrons must travel via tunneling. Tiny shifts in your thinking, and even smaller changes in your energy status in mitochondria can lead to massive alterations of your results and the diseases you get. This is why people get sick today biophysically. People need to know this data. They also need to know that supplementing ubiquinol is highly beneficial for "statin patients only" because it shortens the distance between the same proteins to lower the energy barrier for quantum tunneling of electrons. Nicotine, MB, and red light all shortens the respiratory chain............because they all do some interesting things to the EZ around the mitochondria called the MINOS. Time 8 has massive implications...............http://1.bp.blogspot.com/…/s…/mitofamilyinheritanceimage.gif
  continue reading

3 قسمت

Artwork
iconاشتراک گذاری
 
Manage episode 259263415 series 2654339
محتوای ارائه شده توسط Mito Health Coach Podcast and Mito Health Coach. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Mito Health Coach Podcast and Mito Health Coach یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
Products I've experimented with: Basic Care Nicotine Polacrilex Gum, 2 mg (nicotine), Original Flavor-https://amzn.to/2VQA2ln Pixotine Toothpicks (no additives)- https://pixotine.com/collections/nicotine-toothpicks ---------------------------------------------- Dr. Jack Kruse on nicotine 02.2.2016 (https://www.facebook.com/drjackkruse/posts/1150518161679203): Nicotine has dramatic effect on cytochrome 1 tunneling of electrons: What is that effect? It lowers the % heteroplasmy in mitochondria. Why? It pulses superoxide while shortening the respiratory complex path to stimulate mitophagy to get rid of shitty mitochondria using programs built into to it. If the mitochondria is really bad..........and nicotine won't work you might consider adding methylene blue and a large dash of sunlight to the RPE. FYI: This is a biohack from something I've written. Random thought of the week that should stun you: Half the bestselling drugs in the US target the product of a circadian gene yet pharma ignores chronobiology...........share it with your fellow MD's, family, friends and your patients. For example take the best selling drugs, the statins, do they target circadian cycles? Yep. How? They block the Q cycle moving electrons from cytochrome 1 to 3 to increase the distance electrons can tunnel. Every increase in one Angstroms slows tunneling speeds by a factor of ten. As tunneling speeds slow what occurs? Inflammation and swelling. What is inflammation at its fundamental level? It is the excess of protons and/or loss of electrons at your surfaces. The surfaces being the eye, gut, and skin. pH is a function of proton concentration; low pH = high proton concentration = inflammation = lower EZ in water. Water is a chromophore for red light in the solar spectrum. Once the EZ is formed by proteins filled with electrons touching water, the EZ grows massively when 270 nm UV light hits a surface. If you cannot build an EZ what kind of life do you get? Optimal or suboptimal? Do you think a device designed to deliver purple and red light using surface cooling might have an effect on performance since it acts on this fundamental mechanism? I bet many Quantlet beta testers are already writing down bio-hacks as they read this. The loss of an EZ around the mitochondria for any reason increases the distance between respiratory proteins at the atomic level measured by Angstroms too. DO you see how the link of statins and a loss of EZ are similar? Key take home repeatable point: for every increase of 1 Angstrom, the rate of quantum tunneling of electrons drops ten fold. Do you think that kind of redox drop has a small effect or no effect on bio-energenics in a cell? Or might this be exactly how heteroplasmy develops? Is this why statins cause cognitive delay and metabolic syndrome in tissues with high mitochondrial density? Statins are well known to increase the distance electrons must travel via tunneling. Tiny shifts in your thinking, and even smaller changes in your energy status in mitochondria can lead to massive alterations of your results and the diseases you get. This is why people get sick today biophysically. People need to know this data. They also need to know that supplementing ubiquinol is highly beneficial for "statin patients only" because it shortens the distance between the same proteins to lower the energy barrier for quantum tunneling of electrons. Nicotine, MB, and red light all shortens the respiratory chain............because they all do some interesting things to the EZ around the mitochondria called the MINOS. Time 8 has massive implications...............http://1.bp.blogspot.com/…/s…/mitofamilyinheritanceimage.gif
  continue reading

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