204: Programmable bacteria for antitumor immunity

This Week in Microbiology

Host: Vincent Racaniello

Guests: Nicholas Arpaia and Tal Danino

Vincent meets up with Nick and Tal to explain how they engineered E. coli to lyse within tumors and deliver an antibody that causes tumor regression in mice.

Links for this episode:

• Programmable bacteria induce tumor immunity (Nat Med)
• Synchronized cycles of bacterial lysis (Nature)
• TWiM Listener survey

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