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#430: Delightful Machine Learning Apps with Gradio
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1 #517: Agentic Al Programming with Python 1:17:01

1 #516: Accelerating Python Data Science at NVIDIA 1:05:42

1 #515: Durable Python Execution with Temporal 1:10:54

1 #514: Python Language Summit 2025 1:13:00

1 #513: Stories from Python History 1:08:36

1 #512: Building a JIT Compiler for CPython 1:08:18

1 #510: 10 Polars Tools and Techniques To Level Up Your Data Science 1:02:04

1 #508: Program Your Own Computer with Python 1:11:56

1 #507: Agentic AI Workflows with LangGraph 1:03:59

1 #506: ty: Astral's New Type Checker (Formerly Red-Knot) 1:04:19

1 #505: t-strings in Python (PEP 750) 1:11:59

1 #504: Developer Trends in 2025 1:09:53

1 #503: The PyArrow Revolution 1:08:36

1 #502: Django Ledger: Accounting with Python 1:03:38

1 #501: Marimo - Reactive Notebooks for Python 1:00:35

1 #499: BeeWare and the State of Python on Mobile 1:07:47

1 #498: Algorithms for high performance terminal apps 1:08:16

1 #496: Scaf: Complete blueprint for new Python Kubernetes projects 1:19:34

1 #495: OSMnx: Python and OpenStreetMap 1:01:55

1 #494: Update on Flet: Python + Flutter UIs 1:00:23

1 #493: Quarto: Open-source technical publishing 1:05:01


1 #491: DuckDB and Python: Ducks and Snakes living together 1:02:03


1 #489: Anaconda Toolbox for Excel and more with Peter Wang 1:09:09

1 #487: Building Rust Extensions for Python 1:02:24

1 #486: CSnakes: Embed Python code in .NET 1:02:45

1 #485: Secure coding for Python with SheHacksPurple 1:09:28

1 #483: Reflex Framework: Frontend, Backend, Pure Python 1:03:05

1 #482: Pre-commit Hooks for Python Devs 1:10:20

1 #481: Python Opinions and Zeitgeist with Hynek 1:03:00

1 #477: Awesome Text Tricks with NLP and spaCy 1:03:47

1 #476: Unified Python packaging with uv 1:12:59

1 #475: Python Language Summit 2024 1:01:24

1 #474: Python Performance for Data Science 1:08:23

1 #473: Being a developer with ADHD 1:00:32

1 #472: State of Flask and Pallets in 2024 1:01:33

1 #471: Learning and teaching Pandas 1:04:14

1 #470: Python in Medicine and Patient Care 1:19:04

1 #468: Python Trends Episode 2024 1:05:37

1 #466: Pydantic Performance Tips 1:00:02

1 #465: The AI Revolution Won't Be Monopolized 1:08:46

1 #463: Running on Rust: Granian Web Server 1:04:51

1 #461: Python in Neuroscience and Academic Labs 1:03:37

1 #458: Serverless Python in 2024 1:00:22

1 #457: Software Supply Chain Security with Phylum 1:08:21

1 #456: Building GPT Actions with FastAPI and Pydantic 1:05:20

1 #453: uv - The Next Evolution in Python Packages? 1:14:21

1 #450: Versioning Web APIs in Python 1:02:37

1 #449: Building UIs in Python with FastUI 1:06:16

1 #447: Parallel Python Apps with Sub Interpreters 1:11:09


1 #442: Ultra High Speed Message Parsing with msgspec 1:00:01

1 #441: Python = Syntactic Sugar? 1:07:14

1 #438: Celebrating JupyterLab 4 and Jupyter 7 Releases 1:04:55

1 #437: HTMX for Django Developers (And All of Us) 1:04:50


1 #433: Litestar: Effortlessly Build Performant APIs 1:04:46

1 #431: Visualizing CPython Release Process 1:02:12

1 #429: Taming Flaky Tests 1:09:00

1 #428: Django Trends in 2023 1:09:50

1 #427: 10 Tips and Ideas for the Beginner to Expert Python Journey 1:06:06

1 #426: What's New in PyScript [August 2023] 1:05:00

1 #425: Memray: The endgame Python memory profiler 1:10:28

1 #424: Shiny for Python 1:04:22

1 #423: Solving 10 different simulation problems with Python 1:06:32

1 #422: How data scientists use Python 1:02:16

1 #421: Python at Netflix 1:04:06

1 #419: Debugging Python in Production with PyStack 1:12:23

1 #418: How To Keep A Secret in Python Apps 1:07:11

1 #417: Test-Driven Prompt Engineering for LLMs with Promptimize 1:13:41

1 #412: PEP 711 - Distributing Python Binaries 1:18:20

1 #411: Things I Wish Someone Had Explained To Me Sooner About Python 1:03:45

1 #410: The Intersection of Tabular Data and Generative AI 1:05:38

1 #409: Privacy as Code with Fides 1:08:01

1 #408: Hatch: A Modern Python Workflow 1:02:59

1 #406: Reimagining Python's Packaging Workflows 1:06:41

1 #404: Clean Code in Python 1:04:42

1 #403: Fusion Ignition Breakthrough and Python 1:04:42

1 #401: Migrating 3.8 Million Lines of Python 1:00:57

1 #400: Ruff - The Fast, Rust-based Python Linter 1:03:45

1 #399: Monorepos in Python 1:10:31

1 #397: Evaluating New Open Source Tech Panel 1:03:25

1 #395: Tools for README.md Creation and Maintenance 1:13:31

1 #394: Awesome Jupyter Libraries and Extensions in 2022 1:02:22

1 #393: Space Science with Python 1:03:29

1 #392: Data Science from the Command Line 1:11:04

1 #391: Pyscript powered by MicroPython 1:11:04

1 #390: Mastodon for Python Devs 1:08:41

1 #388: Python 3.11 is here and it's fast 1:06:29

1 #387: Build All the Things with Pants Build System 1:07:50

1 #386: Realtime Web Apps and Dashboards with H2O Wave 1:05:37

1 #384: Python Data Visualization - Where To Start? 1:13:16

1 #383: Textinator and Building macOS Apps with Python 1:06:08

1 #382: Apache Superset: Modern Data Exploration Platform 1:08:16

1 #381: Python Perf: Specializing, Adaptive Interpreter 1:08:53

1 #380: 7 lessons from building a modern TUI framework 1:07:49

1 #379: 17 Libraries You Should Be Using in Django 1:20:32

1 #378: Flet: Flutter apps in Python 1:00:21

1 #377: Python Packaging and PyPI in 2022 1:08:11

1 #376: Pydantic v2 - The Plan 1:18:53

1 #374: PSF Survey in Review 1:02:16

1 #373: Reinventing Azure's Python CLI 1:06:30

1 #372: Applied mathematics with Python 1:15:44

1 #368: End-to-End Web Testing with Playwright 1:13:19

1 #367: Say Hello to PyScript (WebAssembly Python) 1:13:41

1 #366: Optimizing PostgreSQL DB Queries with pgMustard 1:14:06

1 #365: Solving Negative Engineering Problems with Prefect 1:04:10

1 #364: Symbolic Math with Python using SymPy 1:07:52

1 #363: Python for .NET and C# developers 1:06:36

1 #362: Hypermodern Python Projects 1:06:14

1 #360: Removing Python's Dead Batteries (in just 5 years) 1:20:03

1 #359: Lifecycle of a machine learning project 1:07:29

1 #357: Python and the James Webb Space Telescope 1:02:30

1 #356: Tips for ML / AI startups 1:06:27

1 #355: EdgeDB - Building a database in Python 1:18:06

1 #354: Sphinx, MyST, and Python Docs in 2022 1:11:55

1 #353: SQLModel: The New ORM for FastAPI and Beyond 1:18:21

1 #352: Running Python in Production 1:00:12

1 #351: Machine Learning Ethics and Laws Panel 1:10:28

1 #350: Python Steering Council 2021 Retrospective 1:10:18

1 #349: Meet Beanie: A MongoDB ODM + Pydantic 1:20:50

1 #348: Dear PyGui: Simple yet Fast Python GUI Apps 1:01:32

1 #347: Cinder - Specialized Python that Flies 1:11:04

1 #346: 20 Recommended Packages in Review 1:13:43

1 #345: 10 Tips and Tools for Developer Productivity 1:16:39

1 #344: SQLAlchemy 2.0 1:06:19

1 #343: Do Excel things, get notebook Python code with Mito 1:06:14

1 #342: Python in Architecture (as in actual buildings) 1:01:28

1 #340: Time to JIT your Python with Pyjion? 1:13:38

1 #339: Making Python Faster with Guido and Mark 1:01:02

1 #338: Using cibuildwheel to manage the scikit-HEP packages 1:17:44

1 #337: Kedro for Maintainable Data Science 1:03:14

1 #333: State of Data Science in 2021 1:03:59


1 #331: Meet the Python Developer in Residence: Lukasz Langa 1:06:21

1 #330: Apache Airflow Open-Source Workflow with Python 1:07:50

1 #327: Little Automation Tools in Python 1:05:58

1 #325: MicroPython + CircuitPython 1:08:37

1 #324: Gatorade-powered Python APIs 1:12:23

1 #323: Best practices for Docker in production 1:10:47

1 #321: HTMX - Clean, Dynamic HTML Pages 1:12:25

1 #320: Python in the Electrical Energy Sector 1:08:01

1 #318: Measuring your ML impact with CodeCarbon 1:07:43


1 #315: Awesome FastAPI extensions and add ons 1:07:50

1 #314: Ask us about modern Python projects and tools 1:04:40

1 #313: Automate your data exchange with Pydantic 1:00:58

1 #312: Python Apps that Scale to Billions of Users 1:17:09

1 #311: Get inside the .git folder 1:12:16

1 #310: AMA (Ask Me Anything) with Michael 1:02:04

1 #308: Docker for Python Developers (2021 Edition) 1:08:05

1 #307: Python from 1994 to 2021, my how you've grown! 1:11:56

1 #306: Scaling Python and Jupyter with ZeroMQ 1:05:58

1 #305: Python community at Python Discord 1:01:41

1 #304: asyncio all the things with Omnilib 1:00:50

1 #303: Python for Astronomy with Dr. Becky 1:03:56

1 #302: The Data Engineering Landscape in 2021 1:04:33

1 #301: Deploying and running Django web apps in 2021 1:08:34

1 #300: Building a data science startup (panel) 1:06:22

1 #299: Personal search engine with datasette and dogsheep 1:01:42

1 #297: Python year in review (2020 edition) 1:10:23

1 #296: Python in F1 racing 1:05:14


1 #293: Learning how to learn as a developer 1:00:07

1 #292: Pythonic identity (auth in Python ecosystem) 1:05:01

1 #290: Side Hustles for Data Scientists 1:08:04

1 #288: 10 tips to move from Excel to Python 1:03:23

1 #287: Testing without dependencies, mocking in Python 1:03:29

1 #286: Python and ML at NASA Jet Propulsion Laboratory (JPL) 1:07:32

1 #285: Dask as a Platform Service with Coiled 1:11:04

1 #284: Modern and fast APIs with FastAPI 1:06:06

1 #281: Python in Car Racing 1:00:14

1 #279: Modern Python Developer's Toolkit 1:01:29

1 #278: Teach kids Python with real programming and fun games at Code Combat 1:05:28

1 #277: 10 tips every Django developer should know 1:11:57

1 #276: Geekout: Life in the solar system and beyond 1:14:15

1 #271: Unlock the mysteries of time, Python's datetime that is! 1:04:33

1 #265: Why is Python slow? 1:03:26

1 #264: 10 tips every Flask developer should know 1:08:49

1 #263: SEO for developers 1:02:35

1 #262: Build a career in data science 1:11:17

1 #261: Monitoring and auditing machine learning 1:00:42

1 #259: From Academia to Tech Industry and Python 1:00:58

1 #258: Thriving in a remote developer environment 1:07:30


1 #254: A Python mentorship story 1:07:26

1 #253: Moon base geekout 1:22:48

1 #252: What scientific computing can learn from CS 1:10:58

1 #250: Capture over 400x C02 as trees with AI and Python 1:03:07

1 #248: Climate change and your Python code 1:16:34

1 #247: Solo maintainer of open-source in academia 1:05:20

1 #246: Practices of the Python Pro 1:04:08

1 #245: Python packaging landscape in 2020 1:01:54

1 #240: A guided tour of the CPython source code 1:00:25

1 #236: Scaling data science across Python and R 1:00:48

1 #235: Python in your Browser with Skulpt 1:00:20

1 #234: Awesome Python Applications 1:04:36

1 #233: The Masonite Python Web Framework 1:08:18

1 #232: Become a robot developer with Python 1:01:32

1 #231: Advice for freelancing with Python 1:09:41

1 #229: Building advanced Pythonic interviews with docassemble 1:00:43

1 #227: Maintainable data science: Tips for non-developers 1:10:48

1 #226: Building Flask APIs for data scientists 1:09:02

1 #225: Can subinterpreters free us from Python's GIL? 1:10:38

1 #224: 12 lessons from 100 days of web 1:08:54

1 #223: Fun and Easy 2D Games with Python 1:03:59

1 #221: Empowering developers by embedding Python 1:07:04

1 #219: Take a Python tour of duty at the United States Digital Service 1:01:36

1 #215: The software powering Talk Python courses and podcast 1:07:51

1 #214: Dive into CPython 3.8 and beyond 1:00:22

1 #211: Classic CS problems in Python 1:08:46

1 #210: Making the most out of in-person training 1:07:20

1 #209: Inside Python's new governance model 1:07:25

1 #208: Packaging, Making the most of PyCon, and more 1:10:17

1 #204: StaticFrame, like Pandas but safer 1:01:17

1 #201: Choosing JupyterHub and Python over MATLAB 1:03:35

1 #200: Escaping Excel Hell with Python and Pandas 1:06:09

1 #199: Automate all the things with Python at Zapier 1:05:28

1 #198: Catching up with the Anaconda distribution 1:05:14

1 #197: Modern Python Standard Library Cookbook 1:01:25

1 #195: Teaching Python at Apple 1:00:23

1 #194: Learning (and teaching) Python in a vacuum 1:06:50

1 #193: Data Science Year in Review 2018 Edition 1:20:36

1 #191: Python's journey at Microsoft 1:12:27

1 #190: Teaching Django 1:01:43

1 #186: 100 Days of Python in a Magical Universe 1:02:57

1 #185: Creating a Python 3 Culture at Facebook 1:07:46

1 #184: Teaching Python with BBC micro:bit 1:07:38



1 #177: Flask goes 1.0 1:02:22

1 #172: Nuitka: A full Python compiler 1:06:53

1 #169: Becoming a Python content creator 1:06:40

1 #168: 10 Python security holes and how to plug them 1:00:00

1 #166: Continuous delivery with Python 1:09:44

1 #165: Python and the blockchain 1:05:00


1 #159: Inside the new PyPI launch 1:00:41

1 #157: The Journal of Open Source Software 1:04:46

1 #155: Practical steps for moving to Python 3 1:03:26

1 #153: How Python Evolves 1:22:01

1 #151: Gradual Typing of Production Applications 1:09:00

1 #148: Python Book Authors' Panel Discussion 1:02:05

1 #146: Building Alexa Skills with Python and Flask 1:01:07

1 #143: Tuning Python Web App Performance 1:03:23


1 #139: Paths into a data science career 1:02:47

1 #138: Anvil: All web, all Python 1:00:11

1 #136: Secure code lessons from Have I Been Pwned 1:00:18

1 #133: Productivity for developers 1:04:28

1 #132: Contributing to open source 1:04:44

1 #127: Shipping software to users 1:15:10

1 #125: Django REST framework and a new API star is born 1:07:17

1 #121: Microservices in Python 1:05:51

1 #120: Python in Finance 1:07:12


1 #117: Functional Python with Coconut 1:03:31

1 #116: 10 top talks of PyCon 2017 reviewed 1:00:19

1 #112: Geeking out in the golden years 1:07:15

1 #109: MongoDB Applied Design Patterns 1:00:25

1 #108: MicroPython and Open Source Hardware at Adafruit 1:04:43

1 #107: Python concurrency with Curio 1:01:20

1 #100: Python past, present, and future with Guido van Rossum 1:02:33

1 #99: Morepath: Super Powered Python Web Framework 1:04:52

1 #98: Adding concurrency to Django with Django Channels 1:05:14

1 #97: Flask, Django style with Flask-Diamond 1:05:03

1 #93: Spreading Python through the sciences with Software Carpentry 1:01:34

1 #92: Bonus: Python Bytes Crossover: Python 3.6 is going to be awesome, Kite: your friendly co-developing AI 21:00

1 #91: Top 10 Data Science Stories of 2016 1:07:34

1 #90: Data Wrangling with Python 1:01:35


1 #86: Python at StackOverflow 1:10:21

1 #84: Are we failing to fund Python's core infrastructure? 1:05:27

1 #81: Python and Machine Learning in Astronomy 1:02:13

1 #79: Beeware Python Tools 1:22:14

1 #77: 20 Python Libraries You Aren't Using (But Should) 1:16:54


1 #73: Machine learning at the new Microsoft 1:04:43

1 #72: Fashion-driven open source software at Zalando 1:01:18

1 #71: Soft Skills: The software developer's life manual 1:05:32

1 #70: Pythonic cover songs at Loudr 1:01:39

1 #68: Crossing the streams with Podcast.__init__ 1:02:21

1 #66: Faster Python Programs: Measure, Don't Guess 1:04:55

1 #62: San Diego Technology Immersion Group Learns Python 1:09:21

1 #60: Scaling Python to 1000's of cores with Ufora 1:07:28


1 #55: How our engineering environments are killing diversity (and how we can fix it) 1:01:40

1 #54: Enterprise Software with Python 1:07:43

1 #49: Microsoft's JIT-based Python Project: Pyjion 1:03:45

1 #44: Project Jupyter and IPython 1:00:11

1 #38: Continuous Integration and Delivery at Codeship 1:02:50

1 #37: Python Cybersecurity and Penetration Testing 1:04:02

1 #35: Turbogears and the future of Python web frameworks 1:01:15

1 #26: Deploying Python Web Applications (Updated) 1:13:04



1 #22: CPython Internals and Learning Python with pythontutor.com 1:02:35


1 #10: Bringing Python to the Masses with Hosting and DevOps at PythonAnywhere 1:05:38

1 #5: SQLAlchemy and data access in Python 1:02:42



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