Engineering an Open Source CRISPR with Aadyot Bhatnagar

Software Engineering Daily

Player FM - Internet Radio Done Right

40 subscribers

اضافه شده در seven سال پیش

محتوای ارائه شده توسط Software Engineering Daily. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Software Engineering Daily یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

<div class="span index">1</div> <span><a class="" data-remote="true" data-type="html" href="/series/most-innovative-companies">Most Innovative Companies</a></span>

1
Most Innovative Companies

لغو اشتراک

۲ hours پیش۲h ago

لغو اشتراک

هفتگی+

Which companies are on the cutting edge of artificial intelligence? What’s the next major breakthrough in healthcare? How do iconic brands reinvent themselves to appeal to the next generation? Most Innovative Companies is where tech, business, and innovation convene. Join hosts Yasmin Gagne and Josh Christensen as they bring you the latest innovations transforming business and society—and highlights the companies that are reshaping industries and culture.

حدود یک سال پیش 33:50

MP3•خانه قسمت

CRISPR is a powerful tool in biotechnology that allows scientists to precisely edit genes, much like editing lines of code in a computer program. Just as developers can remove or alter specific parts of a code to fix bugs or enhance functionality, CRISPR enables researchers to modify DNA to correct genetic disorders, improve crops, or develop new treatments. The development of CRISPR-based editing was recognized by the Nobel Prize in Chemistry in 2020 awarded to Emmanuelle Charpentier and Jennifer Doudna.

Profluent Bio is an AI-first protein design company that recently developed OpenCRISPR-1, which is an AI-generated, CRISPR-like protein that does not occur in nature. Importantly, the company also released the protein and nucleic acid sequences for OpenCRISPR-1.

Aadyot Bhatnagar is an ML Scientist at Profluent Bio and previously worked at Salesforce. He joins the podcast with Sean Falconer to talk about OpenCRISPR-1 and how it was made.

Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from information visualization to quantum computing. Currently, Sean is Head of Marketing and Developer Relations at Skyflow and host of the podcast Partially Redacted, a podcast about privacy and security engineering. You can connect with Sean on Twitter @seanfalconer.

Please click here to see the transcript of this episode.

Sponsorship inquiries: sponsor@softwareengineeringdaily.com

2104 قسمت

#Jeffmeyerson #Softwaredevelopment #Softwareengineering #News #Tech News #Software Daily

Engineering an Open Source CRISPR with Aadyot Bhatnagar

Software Engineering Daily

40 subscribers

published حدود یک سال پیش

اشتراک گذاری

MP3•خانه قسمت

Aadyot Bhatnagar is an ML Scientist at Profluent Bio and previously worked at Salesforce. He joins the podcast with Sean Falconer to talk about OpenCRISPR-1 and how it was made.

Please click here to see the transcript of this episode.

Sponsorship inquiries: sponsor@softwareengineeringdaily.com

2104 قسمت

#Jeffmeyerson #Softwaredevelopment #Softwareengineering #News #Tech News #Software Daily

All episodes

Software Engineering Daily

1
WayForward Games with Tomm Hulett and Voldi Way 46:02

15 hours پیش46:02

46:02

WayForward is a renowned video game studio that was founded in 1990. The company has developed games for publishers such as Capcom, Konami, and Nintendo and has released their games across major hardware platforms from the last 35 years. They are also the creators of the Shantae series of 2D platformers. WayForward recently developed the latest game in the storied Contra series, called Operation Galuga, which is a reimagining of the original Contra from 1987. Voldi Way is the founder and CEO of WayForward, and Tomm Hulett is a Director at WayForward. They join the show to talk about the history of their studio and developing Contra: Operation Galuga. Joe Nash is a developer, educator, and award-winning community builder, who has worked at companies including GitHub, Twilio, Unity, and PayPal. Joe got his start in software development by creating mods and running servers for Garry’s Mod, and game development remains his favorite way to experience and explore new technologies and concepts. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
CodeRabbit and RAG for Code Review with Harjot Gill 48:42

۳ روز پیش48:42

48:42

One of the most immediate and high-impact applications of LLMs has been in software development. The models can significantly accelerate code writing, but with that increased velocity comes a greater need for thoughtful, scalable approaches to codereview. Integrating AI into the development workflow requires rethinking how to ensure quality,security, and maintainability at scale. CodeRabbit is a startup that brings generative AI into the code review process. It evaluates code quality and security directly within tools like GitHub and VS Code, acting as an AI reviewer that complements existing CI/CD pipelines. Harjot Gill is the founder and CEO of CodeRabbit. He joins the podcast with Kevin Ball to discuss CodeRabbit's architecture. Its multi-model LLM strategy, how it tracks the reasoning trail of agents, managing context windows, lessons from bootstrapping the company, and much more. Full Disclosure: This episode is sponsored by CodeRabbit. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Emulating Retro Games on Modern Consoles with Robin Lavallée and Bill Litshauer 1:01:34

۸ روز پیش1:01:34

1:01:34

Emulating retro games on modern consoles is a growing trend, and allows players to experience classic titles with improved performance, enhanced resolution, and added features like save states and rewinding. However, this process raises many challenging technical questions related to hardware compatibility, performance optimization, rendering, and state management. Implicit Conversions is a company focused on emulating retro PlayStation games on modern consoles. Robin Lavallée is the CEO and Bill Litshauer is the COO at the company. They join the show to talk about the engineering that’s needed to emulate and enhance retro games. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
SED News: Corporate Spies, Postgres, and the Weird Life of Devs Right Now 44:38

10 روز پیش44:38

44:38

Welcome back to SED News, a podcast series from Software Engineering Daily where hosts Gregor Vand and Sean Falconer break down the latest stories in software engineering, Silicon Valley, and wider tech world. In this episode, Gregor and Sean unpack what’s going with Deel and Rippling, explore why Databricks and Snowflake are making big bets on Postgres, and reflect on how AI-powered tools like Cursor are reshaping what it means to be a developer today. They also surface highlights from Hacker News, including Claude’s evolving system prompt and a surprising history of transit cards in Japan and Hong Kong. Gregor Vand is a security-focused technologist, and is the founder and CTO of Mailpass. Previously, Gregor was a CTO across cybersecurity, cyber insurance and general software engineering companies. He has been based in Asia Pacific for almost a decade and can be found via his profile at vand.hk. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
TanStack and the Future of Frontend with Tanner Linsley 55:13

15 روز پیش55:13

55:13

TanStack is an open-source collection of high-performance libraries for JavaScript and TypeScript applications, primarily focused on state management, data fetching, and table utilities. It includes popular libraries like TanStack Query, TanStack Table, and TanStack Router. These libraries emphasize declarative APIs, optimized performance, and developer-friendly features, and they are increasingly popular for modern frontend development. Tanner Linsley is the creator of TanStack and he joins the podcast with Nick Nisi to talk about the project, SSG, type safety, the TanStack Start full-stack React framework, and much more. Nick Nisi is a conference organizer, speaker, and developer focused on tools across the web ecosystem. He has organized and emceed several conferences and has led NebraskaJS for more than a decade. Nick currently works as a developer experience engineer at WorkOS. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
The Challenge of AI Model Evaluations with Ankur Goyal 45:22

17 روز پیش45:22

45:22

Evaluations are critical for assessing the quality, performance, and effectiveness of software during development. Common evaluation methods include code reviews and automated testing, and can help identify bugs, ensure compliance with requirements, and measure software reliability. However, evaluating LLMs presents unique challenges due to their complexity, versatility, and potential for unpredictable behavior. Ankur Goyal is the CEO and Founder of Braintrust Data , which provides an end-to-end platform for AI application development, and has a focus on making LLM development robust and iterative. Ankur previously founded Impira which was acquired by Figma, and he later ran the AI team at Figma. Ankur joins the show to talk about Braintrust and the unique challenges of developing evaluations in a non-deterministic context. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Modern Distributed Applications with Stephan Ewen 41:20

22 روز پیش41:20

41:20

A major challenge with creating distributed applications is achieving resilience, reliability, and fault tolerance. It can take considerable engineering time to address non-functional concerns like retries, state synchronization, and distributed coordination. Event-driven models aim to simplify these issues, but often introduce new difficulties in debugging and operations. Stephan Ewen is the Founder at Restate which aims to simplify modern distributed applications. He is also the co-creator of Apache Flink which is an open-source framework for unified stream-processing and batch-processing. Stephan joins the show with Sean Falconer to talk about distributed applications and his work with Restate. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Crew AI with João Moura 45:08

24 روز پیش45:08

45:08

Agentic AI is seen as a key frontier in artificial intelligence, enabling systems to autonomously act, adapt in real-time, and solve complex, multi-step problems based on objectives and context. Unlike traditional rule-based or generative AI, which are limited to predefined or reactive tasks, agentic AI processes vast information, models uncertainty, and makes context-sensitive decisions, mimicking human-like problem-solving. Crew AI is a platform to build and deploy automated workflows using any LLM and cloud platform. The company has rapidly become one of the most prominent in the field of agentic AI. João Moura is the founder at Crew AI and he joins the show with Sean Falconer to talk about his company. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Chip Design in the AI Era with Thomas Andersen 50:33

29 روز پیش50:33

50:33

Synopsys is a leading electronic design automation company specializing in silicon design and verification, as well as software integrity and security. Their tools are foundational to the creation of modern chips and embedded software, powering everything from smartphones to cars. Chip design is a deeply complex process, often taking months or years and requiring the coordination of thousands of engineers. Now, advances in AI are beginning to transform the field by reducing manual effort, accelerating timelines, and unlocking new design possibilities. Thomas Andersen is the Vice President of AI and Machine Learning at Synopsys , where he has spent over 15 years. He joins the show to talk with Kevin Ball about the evolving role of AI in hardware design, the challenges of training models on tacit, undocumented chip engineering knowledge, the emergence of domain-specific LLMs, and where this fast-moving field is going next. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
OpenTofu with Cory O’Daniel and Malcolm Matalka 48:58

۴ weeks پیش48:58

48:58

OpenTofu is an open-source alternative to Terraform, designed for managing infrastructure as code. It enables users to define, provision, and manage their cloud and on-premises resources using a declarative configuration language. OpenTofu was created to ensure an open and community-driven approach to infrastructure tooling, and it emphasizes compatibility and extensibility for diverse deployment scenarios. Cory O’Daniel is the CEO of Massdriver and he's a founding member of OpenTofu. Malcolm Matalka is a Co-Founder at Terrateam and he’s also a founding member of OpenTofu. They join the podcast to talk about the OpenTofu project. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Mojo and Building a CUDA Replacement with Chris Lattner 56:14

۵ weeks پیش56:14

56:14

Python is the dominant language for AI and data science applications, but it lacks the performance and low-level control needed to fully leverage GPU hardware. As a result, developers often rely on NVIDIA’s CUDA framework, which adds complexity and fragments the development stack. Mojo is a new programming language designed to combine the simplicity of Python with the performance of C and the safety of Rust. It also aims to provide a vendor-independent approach to GPU programming. Mojo is being developed by Chris Lattner , a renowned systems engineer known for his seminal contributions to computer science, including LLVM, the Clang compiler, and the Swift programming language. Chris is the CEO and Co-Founder of Modular AI , the company behind Mojo. In this episode, he joins the show to discuss his engineering journey and his current work on AI infrastructure and the Mojo language. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Building PostgreSQL for the Future with Heikki Linnakangas 42:12

۵ weeks پیش42:12

42:12

PostgreSQL is an open-source database known for its robustness, extensibility, and compliance with SQL standards. Its ability to handle complex queries and maintain high data integrity has made it a top choice for both start-ups and large enterprises. Heikki Linnakangas is a leading developer for the PostgreSQL project, and he's a co-founder at Neon , which provides a serverless platform for spinning up Postgres databases. In this episode, he joins Kevin Ball to talk about why PostgreSQL has become so popular, why he founded Neon, Postgres Core vs. Extensions, the pgvector similarity search for AI applications, and much more. Full Disclosure: This episode is sponsored by Neon. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Security at Coinbase with Philip Martin 47:58

۶ weeks پیش47:58

47:58

Cryptocurrency exchanges face unique security challenges that require specialized threat assessments and planning. Coinbase is a cryptocurrency exchange based in the United States. It was founded in 2012 and has evolved alongside cryptocurrency as a technology. Philip Martin is the Chief Security Officer at Coinbase. Prior to Coinbase, Philip built and led the Incident Response and Security Engineering teams at Palantir and was a US Army counterintelligence agent and Arabic linguist. In this episode, Philip joins the podcast with Gregor Vand to talk about his career and security at Coinbase. Gregor Vand is a security-focused technologist, and is the founder and CTO of Mailpass. Previously, Gregor was a CTO across cybersecurity, cyber insurance and general software engineering companies. He has been based in Asia Pacific for almost a decade and can be found via his profile at vand.hk. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Anthropic and the Model Context Protocol with David Soria Parra 51:30

۶ weeks پیش51:30

51:30

The Model Context Protocol, or MCP, is a new open standard that connects AI assistants to arbitrary data sources and tools, such as codebases, APIs, and content repositories. Instead of building bespoke integrations for each system, developers can use MCP to establish secure, scalable connections between AI models and the data they need. By standardizing this connection layer, MCP enables models to access relevant information in real time, leading to more accurate and context-aware responses. David Soria Parra is a Member of the Technical Staff at Anthropic , where he co-created the Model Context Protocol. He joins the podcast to talk about his career and the future of context-aware AI. Jordi Mon Companys is a product manager and marketer that specializes in software delivery, developer experience, cloud native and open source. He has developed his career at companies like GitLab, Weaveworks, Harness and other platform and devtool providers. His interests range from software supply chain security to open source innovation. You can reach out to him on Twitter at @jordimonpmm Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Grand Theft Auto III on the Dreamcast with Falco Girgis and Stef Kornilios Mitsis Poiitidis 47:39

۷ weeks پیش47:39

47:39

Grand Theft Auto III is a 2001 an open-world action-adventure game developed by Rockstar Games and it had a profound impact on both gaming and popular culture. Its success cemented video games as a dominant form of entertainment and storytelling, and paved the way for future blockbuster franchises. The game was also a technological milestone that redefined what was possible in open-world game design. It was one of the first fully 3D open-world games to offer seamless exploration, blending mission-based gameplay with a living, breathing city. The game was originally released on PlayStation 2 and PC but never had an official Sega Dreamcast version. However, the homebrew community embarked on the goal of porting the game to the Dreamcast, and recently released the port to much acclaim. Falco Girgis and Stef Kornilios Mitsis Poiitidis are developers on the GTA3 Dreamcast port. They join the podcast to talk about the Dreamcast hardware and the heroic task of porting GTA3 to the console. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Polypane with Kilian Valkhof 48:35

۷ weeks پیش48:35

48:35

Polypane is a specialized web development browser that simplifies creating and testing modern websites. A key feature is that it provides multiple screen sizes at once, with synchronized scrolling and interactions, so developers can test different layouts and breakpoints simultaneously. Polypane also focuses on accessibility tools, real-time previews, and debugging features. Kilian Valkhof is the Founder of Polypane which develops the Polypane browser. In this episode he speaks with Josh Goldberg about his career and the creation of his browser. Josh Goldberg is an independent full time open source developer in the TypeScript ecosystem. He works on projects that help developers write better TypeScript more easily, most notably on typescript-eslint: the tooling that enables ESLint and Prettier to run on TypeScript code. Josh regularly contributes to open source projects in the ecosystem such as ESLint and TypeScript. Josh is a Microsoft MVP for developer technologies and the author of the acclaimed Learning TypeScript (O’Reilly), a cherished resource for any developer seeking to learn TypeScript without any prior experience outside of JavaScript. Josh regularly presents talks and workshops at bootcamps, conferences, and meetups to share knowledge on TypeScript, static analysis, open source, and general frontend and web development. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
LiveKit and OpenAI with Russ d’Sa 47:56

۸ weeks پیش47:56

47:56

LiveKit is a platform that provides developers with tools to build real-time audio and video applications at scale. It offers an open-source WebRTC stack for creation of live, interactive experiences like video conferencing, streaming, and virtual events. LiveKit has gained significant attention for its partnership with OpenAI for the Advanced Voice feature. Russ d’Sa is the Founder of LiveKit and has an extensive career in startups. In this episode he joins Sean Falconer to talk about his startup journey, the early days of Y Combinator, LiveKit, WebRTC, LiveKit’s partnership with OpenAI, voice and vision as the future paradigm for computer interaction, and more. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
SED News: CoreWeave IPO, Anthropic’s MCP, and Microsoft Turns 50 46:42

۸ weeks پیش46:42

46:42

Welcome to the pilot episode of SED News, a new podcast series from Software Engineering Daily. Join hosts Gregor Van and Sean Falconer as they break down the week's most important stories in software engineering, machine learning, and developer culture. In this episode, Gregor and Sean discuss the CoreWeave IPO and the company's recent acquisition of weights and biases, dig into Anthropics model context protocol, surface highlights rom hacker news, and reflect on Microsoft turning 50. We'd love to hear what you think of the format. Reach out on BlueSky at @SoftwareDaily or on X at @Software _Daily , @GregorVand , or @seanfalconer . Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Vibe Coding at Heroku with Vish Abrams 52:51

۹ weeks پیش52:51

52:51

AI tools are transforming how developers write code, and although it’s difficult to pinpoint how much code is now AI-generated code, estimates suggest it’s between 20% and 40%, and this figure is poised to grow in the coming years. This evolution has given rise to a new coding paradigm in which developers act as directors, guiding and refining AI-generated solutions rather than manually writing every line of code. This approach was recently termed “vibe coding” by Andrej Karpathy, and it shifts the programmer’s role from detailed coding to overseeing and enhancing AI-produced code. It emphasizes collaborative interaction with AI, blending human creativity with machine efficiency to solve complex problems. Vish Abrams is the Chief Architect at Heroku and previously worked at Oracle and NASA, among other organizations. In this episode, Vish joins the show with Kevin Ball for a wide-ranging conversation about the state of AI-based tools, whether there are limits to vibe coding, AI tools for individuals vs. AI tools for teams, the Model Context Protocol, Heroku’s managed inference service, and much more. Full Disclosure: This episode is sponsored by Heroku (Caffelli) Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Agentic AI at Glean with Eddie Zhou 44:25

۹ weeks پیش44:25

44:25

Glean is a workplace search and knowledge discovery company that helps organizations find and access information across various internal tools and data sources. Their platform uses AI to provide personalized search results to assist members of an organization in retrieving relevant documents, emails, and conversations. The rise of LLM-based agentic reasoning systems now presents new opportunities to build advanced functionality using an organization's internal data. Eddie Zhou is a founding engineer at Glean and previously worked at Google. He joined Sean Falconer to discuss the engineering and design considerations around building agentic tooling to enhance productivity and decision-making. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Turing Award Special: A Conversation with Martin Hellman 42:02

10 weeks پیش42:02

42:02

Martin Hellman is an American cryptographer known for co-inventing public-key cryptography with Whitfield Diffie and Ralph Merkle in the 1970s. Their groundbreaking Diffie-Hellman key exchange method allowed secure communication over insecure channels, laying the foundation for modern encryption protocols. Hellman has also contributed to cybersecurity policy and ethical discussions on nuclear risk. His work has had a lasting impact on cryptography, internet security, and global information protection. Martin received the 2015 Turing Award together with Whitfield Diffie "for inventing and promulgating both asymmetric public-key cryptography, including its application to digital signatures, and a practical cryptographic key-exchange method. " In this episode he joins Gregor Vand to talk about his life and career. Gregor Vand is a security-focused technologist, and is the founder and CTO of Mailpass. Previously, Gregor was a CTO across cybersecurity, cyber insurance and general software engineering companies. He has been based in Asia Pacific for almost a decade and can be found via his profile at vand.hk. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Prometheus and Open-Source Observability with Eric Schabell 46:06

10 weeks پیش46:06

46:06

Modern cloud-native systems are highly dynamic and distributed, which makes it difficult to monitor cloud infrastructure using traditional tools designed for static environments. This has motivated the development and widespread adoption of dedicated observability platforms. Prometheus is an open-source observability tool designed for cloud-native environments. Its strong integration with Kubernetes and pull-based data collection model have driven its popularization in DevOps. However, a common challenge with Prometheus is that it struggles with large data volumes and has limited cost-optimization capabilities. This raises the question of how best to handle Prometheus deployments at large scale. Eric Schabell works in DevRel at Chronosphere where he’s the Director of Community and Developer. He is also a CNCF Ambassador. Eric joins the show with Kevin Ball to talk about metrics collection, time series data, managing Prometheus at scale, tradeoffs between self-hosted vs. managed observability, and more. Full Disclosure: This episode is sponsored by Chronosphere. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Turing Award Special: A Conversation with David Patterson 56:25

11 weeks پیش56:25

56:25

David A. Patterson is a pioneering computer scientist known for his contributions to computer architecture, particularly as a co-developer of Reduced Instruction Set Computing, or RISC, which revolutionized processor design. He has co-authored multiple books, including the highly influential Computer Architecture: A Quantitative Approach. David is a UC Berkeley Pardee professor emeritus, a Google distinguished engineer since 2016, the RIOS Laboratory Director, and the RISC-V International Vice-Chair. He received the 2017 Turing Award together with John L. Hennessy "for pioneering a systematic, quantitative approach to the design and evaluation of computer architectures with enduring impact on the microprocessor industry." In this episode he joins Kevin Ball to talk about his life and career. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Uber’s On-Call Copilot with Paarth Chothani and Eduards Sidorovics 45:23

11 weeks پیش45:23

45:23

At Uber, there are many platform teams supporting engineers across the company, and maintaining robust on-call operations is crucial to keeping services functioning smoothly. The prospect of enhancing the efficiency of these engineering teams motivated Uber to create Genie, which is an AI-powered on-call copilot. Genie assists with on-call management by providing real-time responses to queries, streamlining incident resolution, and facilitating team collaboration. Paarth Chothani is a Staff Software Engineer on the Uber AI Gen AI team. Eduards Sidorovics is a Senior Software Engineer on the Uber AI Platform team. In this episode they join the show with Sean Falconer to talk about the challenges that motivated the creation of Uber Genie, the architecture of Genie, and more. Sean's been an academic, startup founder, and Googler. He has published works covering a wide range of topics from AI to quantum computing. Currently, Sean is an AI Entrepreneur in Residence at Confluent where he works on AI strategy and thought leadership. You can connect with Sean on LinkedIn. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

1
Turing Award Special: A Conversation with John Hennessy 40:03

12 weeks پیش40:03

40:03

John Hennessy is a computer scientist, entrepreneur, and academic known for his significant contributions to computer architecture. He co-developed the RISC architecture, which revolutionized modern computing by enabling faster and more efficient processors. Hennessy served as the president of Stanford University from 2000 to 2016 and later co-founded MIPS Computer Systems and Atheros Communications. Currently, he serves on the board of the Gordon and Betty Moore Foundation, and is chair of the board of Alphabet. John received the 2017 Turing Award "for pioneering a systematic, quantitative approach to the design and evaluation of computer architectures with enduring impact on the microprocessor industry." In this episode he joins Kevin Ball to talk about his life and career. Kevin Ball or KBall, is the vice president of engineering at Mento and an independent coach for engineers and engineering leaders. He co-founded and served as CTO for two companies, founded the San Diego JavaScript meetup, and organizes the AI inaction discussion group through Latent Space. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

Software Engineering Daily

21 weeks پیش1:00:32

1:00:32

Raylib is a lightweight, beginner-friendly, and open-source C library for game development, known for its simplicity and lack of external dependencies. It's designed to streamline the creation of 2D and 3D games, and has an intuitive API for managing graphics, audio, and input. Ramon Santamaria is the Founder and Lead Developer of Raylib . He joins the show with Joe Nash to talk about the Raylib project. Joe Nash is a developer, educator, and award-winning community builder, who has worked at companies including GitHub, Twilio, Unity, and PayPal. Joe got his start in software development by creating mods and running servers for Garry’s Mod, and game development remains his favorite way to experience and explore new technologies and concepts. Please click here to see the transcript of this episode. Sponsorship inquiries: sponsor@softwareengineeringdaily.com…

به Player FM خوش آمدید!

Player FM در سراسر وب را برای یافتن پادکست های با کیفیت اسکن می کند تا همین الان لذت ببرید. این بهترین برنامه ی پادکست است که در اندروید، آیفون و وب کار می کند. ثبت نام کنید تا اشتراک های شما در بین دستگاه های مختلف همگام سازی شود.