64. Tools for Looking into the Brain: Patch-Clamp

Neuroverse

We are launching a new mini-series focusing on experimental methods to study the brain! How do we look at and listen to the activity of neurons, populations of neurons, and the whole brain? In this series, we will be exploring the multitude of techniques and recent advances in technologies to study the brain.

To kick of the series, in this episode we discuss patch-clamping, a type of electrophysiological technique that is used to measure the electrical activity and biophysical properties of individual neurons. Drawing on some of our personal experiences, we discuss the uses and challenges of patch-clamp, what we can discover from it, how different variations can offer different insights, and the future of patch-clamp. ---

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