Accelerating drug discovery with AI: Insights from Isomorphic Labs

Gradient Dissent: Conversations on AI

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اضافه شده در four سال پیش

محتوای ارائه شده توسط Lukas Biewald. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط Lukas Biewald یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

The Sarah Fraser Show

1
SISTER WIVES: The Brown Family Plans Garrison's Funeral, Gives NEW Details About His Passing. Justin Baldoni v Blake Lively UPDATES, First Pictures Of Micah Plath’s Broken Nose Have Surfaced!… 36:16

15 روز پیش36:16

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36:16

DANMMMMM…Have I got a show for you! First, a lot of Sister Wives tea - new rumors have surfaced Janelle Brown is leaving the show. Plus, Gabe Brown gives a life update after losing and tragically finding his brother Garrison dead. Sadly, Garrison took his own life in March 2024. Then we head over to discuss the new Welcome To Plathville tea. The first pictures of Micah Plath have surfaced after being beat up by his brother Issac and it doesn’t look good for the future of his modeling career. Lastly, we discuss the latest in the Justin Baldoni v Blake Lively case, Justin is back on social media and it was the perfect social media return. Timestamps: 00:00:00 - Open and new Sister Wives news 00:05:43 - Janelle Brown leaving the show? Sister Wives Closet is officially closed 00:12:45 - A new pic of Micah Plath’s broken nose has surfaced 00:18:18 - Justin Baldoni back on social media and Taylor Swifts team is pissed at Justin Baldoni MY Go Big Podcasting Courses Are Here! Purchase Go Big Podcasting and learn to start, monetize, and grow your own podcast. USE CODE: MOM15 for 15% OFF (code expires May 11th, 2025) **SHOP my Amazon Marketplace - especially if you're looking to get geared-up to start your own Podcast!!!** https://www.amazon.com/shop/thesarahfrasershow Show is sponsored by: Download Cash App & sign up! Use our exclusive referral code TSFS in your profile, send $5 to a friend within 14 days, and you’ll get $10 dropped right into your account. Terms apply Horizonfibroids.com get rid of those nasty fibroids Gopurebeauty.com science backed skincare from head to toe, use code TSFS at checkout for 25% OFF your order Nutrafol.com use code TSFS for FREE shipping and $10 off your subscription Rula.com/tsfs to get started today. That’s R-U-L-A dot com slash tsfs for convenient therapy that’s covered by insurance. SkylightCal.com/tsfs for $30 OFF your 15 inch calendar Quince.com/tsfs for FREE shipping on your order and 365 day returns Warbyparker.com/tsfs make an appointment at one of their 270 store locations and head to the website to try on endless pairs of glasses virtually and buy your perfect pair Follow me on Instagram/Tiktok: @thesarahfrasershow ***Visit our Sub-Reddit: reddit.com/r/thesarahfrasershow for ALL things The Sarah Fraser Show!!!*** Advertise on The Sarah Fraser Show: thesarahfrasershow@gmail.com Got a juicy gossip TIP from your favorite TLC or Bravo show? Email: thesarahfrasershow@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices…

حدود یک سال پیش 1:10:23

MP3•خانه قسمت

In this episode of Gradient Dissent, Isomorphic Labs Chief AI Officer Max Jaderberg, and Chief Technology Officer Sergei Yakneen join our host Lukas Biewald to discuss the advancements in biotech and drug discovery being unlocked with machine learning.

With backgrounds in advanced AI research at DeepMind, Max and Sergei offer their unique insights into the challenges and successes of applying AI in a complex field like biotechnology. They share their journey at Isomorphic Labs, a company dedicated to revolutionizing drug discovery with AI. In this episode, they discuss the transformative impact of deep learning on the drug development process and Isomorphic Labs' strategy to innovate from molecular design to clinical trials.

You’ll come away with valuable insights into the challenges of applying AI in biotech, the role of AI in streamlining the drug discovery pipeline, and peer into the future of AI-driven solutions in healthcare.

Connect with Sergei Yakneen & Max Jaderberg:

https://www.linkedin.com/in/maxjaderberg/

https://www.linkedin.com/in/yakneensergei/

https://twitter.com/SergeiIakhnin

https://twitter.com/maxjaderberg

Follow Weights & Biases:

https://twitter.com/weights_biases

https://www.linkedin.com/company/wandb

124 قسمت

#Machine Learning #Tech #Business #Lukas Biewald

Accelerating drug discovery with AI: Insights from Isomorphic Labs

Gradient Dissent: Conversations on AI

published حدود یک سال پیش

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MP3•خانه قسمت

Connect with Sergei Yakneen & Max Jaderberg:

https://www.linkedin.com/in/maxjaderberg/

https://www.linkedin.com/in/yakneensergei/

https://twitter.com/SergeiIakhnin

https://twitter.com/maxjaderberg

Follow Weights & Biases:

https://twitter.com/weights_biases

https://www.linkedin.com/company/wandb

124 قسمت

#Machine Learning #Tech #Business #Lukas Biewald

همه قسمت ها

Gradient Dissent: Conversations on AI

1
From Pharma to AGI Hype, and Developing AI in Finance: Martin Shkreli’s Journey 1:30:19

۸ روز پیش1:30:19

1:30:19

In this episode of Gradient Dissent, Lukas Biewald talks with Martin Shkreli — the infamous "pharma bro" turned founder — about his path from hedge fund manager and pharma CEO to convicted felon and now software entrepreneur. Shkreli shares his side of the drug pricing controversy, reflects on his prison experience, and explains how he rebuilt his life and business after being "canceled." They dive deep into AI and drug discovery, where Shkreli delivers a strong critique of mainstream approaches. He also talks about his latest venture in finance software, building Godel Terminal “a Vim for traders", and why he thinks the AI hype cycle is just beginning. It's a wide-ranging and candid conversation with one of the most controversial figures in tech and biotech. Follow Martin Shkreli on Twitter Godel Terminal: https://godelterminal.com/ Follow Weights & Biases on Twitter https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

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Inside Cursor: The future of AI coding with Co-founder Sualeh Asif 49:36

29 روز پیش49:36

49:36

In this episode of Gradient Dissent, host Lukas Biewald talks with Sualeh Asif, the CPO and co-founder of Cursor, one of the fastest-growing and most loved AI-powered coding platforms. Sualeh shares the story behind Cursor’s creation, the technical and design decisions that set it apart, and how AI models are changing the way we build software. They dive deep into infrastructure challenges, the importance of speed and user experience, and how emerging trends in agents and reasoning models are reshaping the developer workflow. Sualeh also discusses scaling AI inference to support hundreds of millions of requests per day, building trust through product quality, and his vision for how programming will evolve in the next few years. ⏳Timestamps: 00:00 How Cursor got started and why it took off 04:50 Switching from Vim to VS Code and the rise of CoPilot 08:10 Why Cursor won among competitors: product philosophy and execution 10:30 How user data and feedback loops drive Cursor’s improvements 12:20 Iterating on AI agents: what made Cursor hold back and wait 13:30 Competitive coding background: advantage or challenge? 16:30 Making coding fun again: latency, flow, and model choices 19:10 Building Cursor’s infrastructure: from GPUs to indexing billions of files 26:00 How Cursor prioritizes compute allocation for indexing 30:00 Running massive ML infrastructure: surprises and scaling lessons 34:50 Why Cursor chose DeepSeek models early 36:00 Where AI agents are heading next 40:07 Debugging and evaluating complex AI agents 42:00 How coding workflows will change over the next 2–3 years 46:20 Dream future projects: AI for reading codebases and papers 🎙 Get our podcasts on these platforms: Apple Podcasts: https://wandb.me/apple-podcasts Spotify: https://wandb.me/spotify YouTube: https://wandb.me/youtube Follow Weights & Biases: https://x.com/weights_biases https://www.linkedin.com/company/wandb…

Gradient Dissent: Conversations on AI

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Inside the Dark Web, AI and Cybersecurity with Christopher Ahlberg CEO of Recorded Future 50:15

۷ weeks پیش50:15

50:15

In this episode of Gradient Dissent, host Lukas Biewald talks with Christopher Ahlberg, CEO of Recorded Future, a pioneering cybersecurity company leveraging AI to provide intelligence insights. Christopher shares his fascinating journey from founding data visualization startup Spotfire to building Recorded Future into an industry leader, eventually leading to its acquisition by Mastercard. They dive into gripping stories of cyber espionage, including how Recorded Future intercepted a hacker selling access to the U.S. Electoral Assistance Commission. Christopher also explains why the criminal underworld has shifted to platforms like Telegram, how AI is transforming both cyber threats and defenses, and the real-world implications of becoming an "undesirable enemy" of the Russian state. This episode offers unique insights into cybersecurity, AI-driven intelligence, entrepreneurship lessons from a two-time founder, and what happens when geopolitical tensions intersect with cutting-edge technology. A must-listen for anyone interested in cybersecurity, artificial intelligence, or the complex dynamics shaping global security. 🎙 Get our podcasts on these platforms: Apple Podcasts: https://wandb.me/apple-podcast s Spotify: https://wandb.me/spotify YouTube: https://wandb.me/youtube Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb…

Gradient Dissent: Conversations on AI

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AI, autonomy, and the future of naval warfare with Captain Jon Haase, United States Navy 1:01:32

۹ weeks پیش1:01:32

1:01:32

In this episode of Gradient Dissent, host Lukas Biewald speaks with Captain Jon Haase, United States Navy about real-world applications of AI and autonomy in defense. From underwater mine detection with autonomous vehicles to the ethics of lethal AI systems, this conversation dives into how the U.S. military is integrating AI into mission-critical operations — and why humans will always be at the center of warfighting. They explore the challenges of underwater autonomy, multi-agent collaboration, cybersecurity, and the growing role of large language models like Gemini and Claude in the defense space. Essential listening for anyone curious about military AI, defense tech, and the future of autonomous systems. ✅ *Subscribe to Weights & Biases* → https://bit.ly/45BCkYz 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

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The rise of AI agents 49:09

13 weeks پیش49:09

49:09

In this episode of Gradient Dissent, host Lukas Biewald sits down with João Moura, CEO & Founder of CrewAI, one of the leading platforms enabling AI agents for enterprise applications. Joe shares insights into how AI agents are being successfully deployed in over 40% of Fortune 500 companies, what tools these agents rely on, and how software companies are adapting to an agentic world. They also discuss: What defines a true AI agent versus simple automation How AI agents are transforming business processes in industries like finance, insurance, and software The evolving business models for APIs as AI agents become the dominant software users What the next breakthroughs in agentic AI might look like in 2025 and beyond If you're curious about the cutting edge of AI automation, enterprise AI adoption, and the real impact of multi-agent systems, this episode is packed with essential insights.…

Gradient Dissent: Conversations on AI

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R1, OpenAI’s o3, and the ARC-AGI Benchmark: Insights from Mike Knoop 1:12:01

16 weeks پیش1:12:01

1:12:01

In this episode of Gradient Dissent , host Lukas Biewald sits down with Mike Knoop , Co-founder and CEO of Ndea , a cutting-edge AI research lab. Mike shares his journey from building Zapier into a major automation platform to diving into the frontiers of AI research. They discuss DeepSeek’s R1, OpenAI’s O-series models, and the ARC Prize , a competition aimed at advancing AI’s reasoning capabilities. Mike explains how program synthesis and deep learning must merge to create true AGI , and why he believes AI reliability is the biggest hurdle for automation adoption. This conversation covers AGI timelines, research breakthroughs, and the future of intelligent systems , making it essential listening for AI enthusiasts, researchers, and entrepreneurs. Mentioned Show Notes: https://ndea.com https://arcprize.org/blog/r1-zero-r1-results-analysis https://arcprize.org/blog/oai-o3-pub-breakthrough 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Connect with Mike Knoop" @mikeknoop Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

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DeepSeek, Stargate and AI's $600 Billion Question with Sequoia's David Cahn 58:16

17 weeks پیش58:16

58:16

In this episode of Gradient Dissent , host Lukas Biewald sits down with David Cahn, partner at Sequoia Capital, for a compelling discussion on the dynamic world of AI investments. They dive into recent developments, including DeepSeek and Stargate, exploring their implications for the AI industry. Drawing from his articles, "AI's $200 Billion Question" and "AI's $600 Billion Question," David unpacks the financial challenges and opportunities surrounding AI infrastructure spending and the staggering revenue required to sustain these investments. Together, they examine the competitive strategies of cloud providers, the transformative impact of AI on business models, and predictions for the next wave of AI-driven growth. This episode offers an in-depth look at the crossroads of AI innovation and financial strategy. Mentioned Articles: AI’s $200B Question AI’s $600B Question 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Connect with David Cahn: @DavidCahn6 Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

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Building the future of collaborative AI development with Akshay Agrawal 41:03

20 weeks پیش41:03

41:03

In this episode of Gradient Dissent , Akshay Agrawal, Co-Founder of Marimo, joins host Lukas Biewald to discuss the future of collaborative AI development. They dive into how Marimo is enabling developers and researchers to collaborate seamlessly on AI projects, the challenges of scaling AI tools, and the importance of fostering open ecosystems for innovation. Akshay shares insights into building a platform that empowers teams to iterate faster and solve complex AI challenges together. Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

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Evaluating LLMs with Chatbot Arena and Joseph E. Gonzalez 55:32

23 weeks پیش55:32

55:32

In this episode of Gradient Dissent, Joseph E. Gonzalez, EECS Professor at UC Berkeley and Co-Founder at RunLLM, joins host Lukas Biewald to explore innovative approaches to evaluating LLMs. They discuss the concept of vibes-based evaluation, which examines not just accuracy but also the style and tone of model responses, and how Chatbot Arena has become a community-driven benchmark for open-source and commercial LLMs. Joseph shares insights on democratizing model evaluation, refining AI-human interactions, and leveraging human preferences to improve model performance. This episode provides a deep dive into the evolving landscape of LLM evaluation and its impact on AI development. 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

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AI’s breakthrough in weather forecasting with Brightband’s Julian Green 49:58

26 weeks پیش49:58

49:58

In this episode of Gradient Dissent, Julian Green, Co-founder & CEO of Brightband, joins host Lukas Biewald to discuss how AI is transforming weather forecasting and climate solutions. They explore Brightband's innovative approach to using AI for extreme weather prediction, the shift from physics-based models to AI-driven forecasting, and the potential for democratizing weather data. Julian shares insights into building trust in AI for critical decisions, navigating the challenges of deep tech entrepreneurship, and the broader implications of AI in mitigating climate risks. This episode delves into the intersection of AI and Earth systems, highlighting its transformative impact on weather and climate decision-making. 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Connect with Julian Green: @juliangreensf Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

1
What’s the path to AGI? A conversation with Turing Co-founder and CEO Jonathan Siddharth 54:48

29 weeks پیش54:48

54:48

In this episode of Gradient Dissent, Jonathan Siddharth, CEO & Co-Founder of Turing, joins host Lukas Biewald to discuss the path to AGI. They explore how Turing built a "developer cloud" of 3.7 million engineers to power AGI training, providing high-quality code and reasoning data to leading AI labs. Jonathan shares insights on Turing’s journey, from building coding datasets to solving enterprise AI challenges and enabling human-in-the-loop solutions. This episode offers a unique perspective on the intersection of human intelligence and AGI, with an eye on the expansion of new domains beyond coding. ✅ *Subscribe to Weights & Biases* → https://bit.ly/45BCkYz 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Connect with Jonathan Siddharth: https://www.linkedin.com/in/jonsid/ Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

1
Vercel’s CEO & Founder Guillermo Rauch on the impact of AI on Web Development and Front End Engineering 56:57

31 weeks پیش56:57

56:57

In this episode of Gradient Dissent, Guillermo Rauch, CEO & Founder of Vercel, joins host Lukas Biewald for a wide ranging discussion on how AI is changing web development and front end engineering. They discuss how Vercel’s v0 expert AI agent is generating code and UI based on simple ChatGPT-like prompts, the importance of releasing daily for AI applications, and the changing landscape of frontier model performance between open and closed models. Listen on Apple Podcasts: http://wandb.me/apple-podcasts Listen on Spotify: http://wandb.me/spotify Subscribe to Weights & Biases: https://bit.ly/45BCkYz Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Connect with Guillermo Rauch: https://www.linkedin.com/in/rauchg/ https://x.com/rauchg Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

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Snowflake’s CEO Sridhar Ramaswamy on 700+ LLM enterprise use cases 55:42

33 weeks پیش55:42

55:42

In this episode of Gradient Dissent, Snowflake CEO Sridhar Ramaswamy joins host Lukas Biewald to explore how AI is transforming enterprise data strategies. They discuss Sridhar's journey from Google to Snowflake, diving into the evolving role of foundation models, Snowflake’s AI strategy, and the challenges of scaling AI in business. Sridhar also shares his thoughts on leadership, rapid iteration, and creating meaningful AI solutions for enterprise clients. Tune in to discover how Snowflake is driving innovation in the AI and data space. Connect with Sridhar Ramaswamy: https://www.linkedin.com/in/sridhar-ramaswamy/ Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

1
Elevating ML Infrastructure with Modal Labs CEO Erik Bernhardsson 49:39

35 weeks پیش49:39

49:39

In this episode of Gradient Dissent, Erik Bernhardsson, CEO & Founder of Modal Labs, joins host Lukas Biewald to discuss the future of machine learning infrastructure. They explore how Modal is enhancing the developer experience, handling large-scale GPU workloads, and simplifying cloud execution for data teams. If you’re into AI, data pipelines, or building robust ML systems, this episode is packed with valuable insights! 🎙 *Listen on Apple Podcasts*: http://wandb.me/apple-podcasts 🎙 *Listen on Spotify*: http://wandb.me/spotify ✅ *Subscribe to Weights & Biases* → https://bit.ly/45BCkYz 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Connect with Erik Bernhardsson: https://www.linkedin.com/in/erikbern/ https://x.com/bernhardsson Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

Gradient Dissent: Conversations on AI

1
From No-Code to AI-Powered Apps with Airtable’s Howie Liu 1:12:57

37 weeks پیش1:12:57

1:12:57

In this episode of Gradient Dissent, Howie Lou, CEO of Airtable, joins host Lukas Biewald to dive into Airtable's transformation from a no-code app builder to a platform capable of supporting complex AI-driven workflows. They discuss the strategic decisions that propelled Airtable's growth, the challenges of scaling AI in enterprise settings, and the future of AI in business operations. Discover how Airtable is reshaping digital transformation and why flexibility and innovation are key in today's tech landscape. Tune in now to learn about the evolving role of AI in business and product development. 🎙 *Listen on Apple Podcasts*: http://wandb.me/apple-podcasts 🎙 *Listen on Spotify*: http://wandb.me/spotify ✅ *Subscribe to Weights & Biases* → https://bit.ly/45BCkYz 🎙 Get our podcasts on these platforms: Apple Podcasts: http://wandb.me/apple-podcasts Spotify: http://wandb.me/spotify Google: http://wandb.me/gd_google YouTube: http://wandb.me/youtube Connect with Howie Liu: https://www.linkedin.com/in/howieliu/ https://x.com/howietl Follow Weights & Biases: https://twitter.com/weights_biases https://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server: https://discord.gg/CkZKRNnaf3…

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Accelerating drug discovery with AI: Insights from Isomorphic Labs

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Accelerating drug discovery with AI: Insights from Isomorphic Labs