Redefining chronic pain treatment

Beyond Biotech - the podcast from Labiotech

Doloromics is a precision neuropharmaceuticals company. It was set up four years ago, to use newer technologies, particularly in the omics space, to take advantage of different single-cell transcriptomic technologies or proteomic technologies to better understand the progression of neurological diseases like chronic pain.

The Doloromics pipeline is built upon a proprietary discovery and validation platform DOLOReS.
Jackson Brougher, chief scientific officer and co-founder of Doloromics, is our guest on this week’s Beyond Biotech podcast.

00:46-04:41: About Doloromics
04:41-07:09: What is chronic pain?
07:09-08:30: How challenging is the subjectivity of pain?
08:30-11:04: What is nociception?
11:04-12:23: The challenges of treating pain
12:23-16:35: Is chronic pain a disease?
16:35-19:57: What is VX-548?
19:57-22:17: Monoclonal antibodies and CGRPs
22:17-26:22: How have recent advances in genomic technologies advanced the understanding of pain?
26:22-31:03: What is the DOLOReS platform?
31:03-32:37: Delivery methods
32:37-33:55: Keeping costs low
33:55-34:58: Next steps

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1. Redefining chronic pain treatment (00:00:00)

2. About Doloromics (00:00:46)

3. What is chronic pain?
 (00:04:41)

4. How challenging is the subjectivity of pain?
 (00:07:09)

5. What is nociception? (00:08:30)

6. The challenges of treating pain (00:11:04)

7. Is chronic pain a disease? (00:12:23)

8. What is VX-548?
 (00:16:35)

9. Monoclonal antibodies and CGRPs
 (00:19:57)

10. How have recent advances in genomic technologies advanced the understanding of pain?
 (00:22:17)

11. What is the DOLOReS platform?
 (00:26:22)

12. Delivery methods (00:31:03)

13. Keeping costs low (00:32:37)

14. Next steps (00:33:55)