49ers in Five: Isaac Guerendo WILL play tonight vs. the Rams

The Gold Standard: San Francisco 49ers Podcast Network

49ers in Five: Isaac Guerendo WILL play tonight vs. the Rams

San Francisco 49ers RB Isaac Guerendo will try and play on a foot sprain against the Los Angeles Rams, according to Adam Schefter. Plus, George Kittle predicts a breakout game for Deebo Samuel, and Brock Purdy scouts the Rams defense.

One Thing to Read: https://www.espn.com/nfl/insider/story/_/id/42910575/2025-offseason-moves-fix-49ers-bengals-cowboys-jets-trades-cuts-firings-signings

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