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محتوای ارائه شده توسط by SC Zoomers and By SC Zoomers. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط by SC Zoomers and By SC Zoomers یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal
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Unraveling Addiction: What the Brain and Hormones Can Teach Us About Ourselves

12:39
 
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Manage episode 460371933 series 3602245
محتوای ارائه شده توسط by SC Zoomers and By SC Zoomers. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط by SC Zoomers and By SC Zoomers یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

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Today, we dive into the complex world of adolescent substance use, exploring groundbreaking research that reveals how biological factors influence risk susceptibility. With insights from recent studies published in *ScienceDaily* and *Neuroscience News*, we uncover the intricate connections between brain structure, early substance initiation, and the role of estrogen in binge drinking behavior among females.
In this episode, we begin by examining a significant study from the Adolescent Brain Cognitive Development (ABCD) Study—the largest longitudinal study of its kind in the U.S. Here, researchers discovered distinct brain structure differences in adolescents who began using substances like alcohol, nicotine, or cannabis before age 15. We discuss how variations in cortical thickness, surface area, and volume in critical brain regions, particularly the cortex, may predispose these adolescents to higher risks of substance use.
Dr. Nora Volkow, director of NIDA, emphasizes that while brain structure can shed light on risk factors, it is not a definitive predictor of substance use. Some of these structural differences were evident even before any reported substance use, hinting at a complex interplay of genetics, environmental influences, and brain architecture that contributes to individual resilience and vulnerability.
The conversation then shifts to the fascinating relationship between estrogen and binge drinking in females. A preclinical study published in *Nature Communications* reveals a direct link between high estrogen levels during specific phases of the estrous cycle in female mice and increased binge drinking behavior. We explore how estrogen binds rapidly to neuronal receptors, leading to immediate behavioral changes—a breakthrough that could redefine how we understand hormonal influences on addiction.
Dr. Kristen Pleil from Weill Cornell Medicine highlights this novel mechanism, suggesting that estrogen's quick impact on behavior opens new avenues for intervention. With a better understanding of how biological factors like estrogen interact with substance use, we discuss the potential for personalized prevention strategies tailored to individuals’ unique vulnerabilities.
Sources:

Brain structure differences are associated with early use of substances among adolescents

Support the show

About SCZoomers:
https://www.facebook.com/groups/1632045180447285
https://x.com/SCZoomers
https://mstdn.ca/@SCZoomers
https://bsky.app/profile/safety.bsky.app

Spoken word, short and sweet, with rhythm and a catchy beat.
http://tinyurl.com/stonefolksongs
Curated, independent, moderated, timely, deep, gentle, evidenced-based, clinical & community information regarding COVID-19. Since 2017, it has focused on Covid since Feb 2020, with Multiple Stores per day, hence a large searchable base of stories to date. More than 4000 stories on COVID-19 alone. Hundreds of stories on Climate Change.
Zoomers of the Sunshine Coast is a news organization with the advantages of deeply rooted connections within our local community, combined with a provincial, national and global following and exposure. In written form, audio, and video, we provide evidence-based and referenced stories interspersed with curated commentary, satire and humour. We reference where our stories come from and who wrote, published, and even inspired them. Using a social media platform means we have a much higher degree of interaction with our readers than conventional media and provides a significant amplification effect, positively. We expect the same courtesy of other media referencing our stories.

  continue reading

153 قسمت

Artwork
iconاشتراک گذاری
 
Manage episode 460371933 series 3602245
محتوای ارائه شده توسط by SC Zoomers and By SC Zoomers. تمام محتوای پادکست شامل قسمت‌ها، گرافیک‌ها و توضیحات پادکست مستقیماً توسط by SC Zoomers and By SC Zoomers یا شریک پلتفرم پادکست آن‌ها آپلود و ارائه می‌شوند. اگر فکر می‌کنید شخصی بدون اجازه شما از اثر دارای حق نسخه‌برداری شما استفاده می‌کند، می‌توانید روندی که در اینجا شرح داده شده است را دنبال کنید.https://fa.player.fm/legal

Send us a text

Today, we dive into the complex world of adolescent substance use, exploring groundbreaking research that reveals how biological factors influence risk susceptibility. With insights from recent studies published in *ScienceDaily* and *Neuroscience News*, we uncover the intricate connections between brain structure, early substance initiation, and the role of estrogen in binge drinking behavior among females.
In this episode, we begin by examining a significant study from the Adolescent Brain Cognitive Development (ABCD) Study—the largest longitudinal study of its kind in the U.S. Here, researchers discovered distinct brain structure differences in adolescents who began using substances like alcohol, nicotine, or cannabis before age 15. We discuss how variations in cortical thickness, surface area, and volume in critical brain regions, particularly the cortex, may predispose these adolescents to higher risks of substance use.
Dr. Nora Volkow, director of NIDA, emphasizes that while brain structure can shed light on risk factors, it is not a definitive predictor of substance use. Some of these structural differences were evident even before any reported substance use, hinting at a complex interplay of genetics, environmental influences, and brain architecture that contributes to individual resilience and vulnerability.
The conversation then shifts to the fascinating relationship between estrogen and binge drinking in females. A preclinical study published in *Nature Communications* reveals a direct link between high estrogen levels during specific phases of the estrous cycle in female mice and increased binge drinking behavior. We explore how estrogen binds rapidly to neuronal receptors, leading to immediate behavioral changes—a breakthrough that could redefine how we understand hormonal influences on addiction.
Dr. Kristen Pleil from Weill Cornell Medicine highlights this novel mechanism, suggesting that estrogen's quick impact on behavior opens new avenues for intervention. With a better understanding of how biological factors like estrogen interact with substance use, we discuss the potential for personalized prevention strategies tailored to individuals’ unique vulnerabilities.
Sources:

Brain structure differences are associated with early use of substances among adolescents

Support the show

About SCZoomers:
https://www.facebook.com/groups/1632045180447285
https://x.com/SCZoomers
https://mstdn.ca/@SCZoomers
https://bsky.app/profile/safety.bsky.app

Spoken word, short and sweet, with rhythm and a catchy beat.
http://tinyurl.com/stonefolksongs
Curated, independent, moderated, timely, deep, gentle, evidenced-based, clinical & community information regarding COVID-19. Since 2017, it has focused on Covid since Feb 2020, with Multiple Stores per day, hence a large searchable base of stories to date. More than 4000 stories on COVID-19 alone. Hundreds of stories on Climate Change.
Zoomers of the Sunshine Coast is a news organization with the advantages of deeply rooted connections within our local community, combined with a provincial, national and global following and exposure. In written form, audio, and video, we provide evidence-based and referenced stories interspersed with curated commentary, satire and humour. We reference where our stories come from and who wrote, published, and even inspired them. Using a social media platform means we have a much higher degree of interaction with our readers than conventional media and provides a significant amplification effect, positively. We expect the same courtesy of other media referencing our stories.

  continue reading

153 قسمت

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