DNA Methylation, Lateral Ventricular Volume, and Psychiatric Risk for Schizophrenia

Association for Child and Adolescent Mental Health (ACAMH)

DOI: 10.13056/acamh.25592
In this Papers Podcast, Dr. Charlotte Cecil and Dr. Mannan Luo discuss their co-authored JCPP paper ‘DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study’ (https://doi.org/10.1111/jcpp.13866).
There is an overview of the paper, methodology, key findings, and implications for practice.
Discussion points include:

• Definitions of ‘lateral ventricular volume enlargement’ and ‘epigenetics process of DNA methylation’.
• The advantage of capturing DNA methylation at different life stages.
• How this approach will further knowledge in this field.
• Implications of the findings for researchers, and clinicians.
• Potential follow-up studies.

In this series, we speak to authors of papers published in one of ACAMH’s three journals. These are The Journal of Child Psychology and Psychiatry (JCPP); The Child and Adolescent Mental Health (CAMH) journal; and JCPP Advances.